Lab News

June 2018 Michelle Baack was invited to serve as a member of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NIH-NICHD) Strategic Planning Work Group. This group will help develop a new strategic plan to advance scientific goals, training, career development and partnership priorities to maximize the NICHD’s commitment to the health of children.

March 2018 Michelle Baack received the USD Sanford School of Medicine Class of 1954 Warren L. Jones, MD Faculty Award. This award recognizes an outstanding medical school faculty member who upholds the tradition of excellence in teaching basic medical science.

February 2018 Michelle Baack and Randy Faustino received a research grant from the Sanford Health Foundation for their project to determine the optimal composition of the extracellular matrix for generation of cardiac tissue from human umbilical cord-derived mesenchymal stem cells.

November 2017 Dr. Michelle Baack published an article in Pediatric Research showing evidence that a maternal diet high in saturated fat may influence the health of the developing offspring by altering placental lipid accumulation and composition. "Placental lipid processing in response to a maternal high-fat diet and diabetes in rats."

October 2017 Dr. Michelle Baack was an invited guest speaker at the Exercise and Nutrition Science Seminar Series at the University of New York at Buffalo in Buffalo, NY. Dr. Baack discussed the impact of maternal dietary fat intake on the developing fetus and breastfeeding baby in her talk titled "Fats and the fetus: you are what your mother eats."

September 2017 Dr. Michelle Baack was featured on Keloland news to discuss ongoing projects to understand, prevent, and treat newborn diseases. Dr. Baack discussed Sanford's involvement as one of 15 NIH-selected sites comprising the Neonatal Research Network which allows our neurologists to provide pre-term babies with the newest and most promising therapies. http://www.keloland.com/news/article/featured-stories/inside-keloland-red-cross-volunteers-sanford-studies

September 2017 Dr. Michelle Baack attended the annual meeting of the Perinatal Research Society (PRS) in Atlanta, GA. PRS fosters scientific interchange among people with research interests in perinatal medicine and developmental biology. Dr. Baack was invited to join PRS as an associate member in 2015 because of her expertise in neonatology and developmental origins of health and disease.

August 2017 Dr. Michelle Baack along with Dr. Alexei Savinov received a Mayo Collaboration grant for their project "Is the heterogenic mother mitochondrial DNA genome a cause of rejection in transplanted organs from cloned animals?"

July 2017 Dr. Michelle Baack was invited to present her research findings during the FASEB Science Research Conference on Origins and Benefits of Biologically Active Components in Human Milk in Lisbon, Portugal. Dr. Baack addressed the importance of essential fats found in breast milk that improve life-long health through better lipid balance during early development. "DHA during early development - Building better brains and beyond."

July 2017 Dr. Michelle Baack was interviewed by KELO about Sanford's participation in the Neonatal Research Network and how research leads to advancements in care for high-risk babies. Dr. Baack was joined by a family including their 2-year old daughter who was a very premature infant in the Boekelheide NICU. http://www.keloland.com/news/article/healthbeat/parents-left-with-positive-experience-after-time-at-nicu

May 2017 Dr. Michelle Baack participated in the Eunice Kennedy Schriver National Institute of Child Health and Human Development (NICHD) - Neonatal Research Network (NRN) Steering Committee meeting at the NIH in Bethesda, MD. The Steering Committee guides neonatal research and clinical trials at fifteen NIH-approved, tertiary care NICUs across the nation.

May 2017 Dr. Michelle Baack, published a research article in Nutrients discovering that a maternal high-fat diet during pregnancy causes epigenetic reprogramming of cardiac metabolism and heart disease in offspring of diabetic and obese mothers. "Fat diet affects histone modification of cardiometabolic genes in newborn rats". 

March 2017 Michelle Baack, MD, served as a content expert for an episode of "On Call with the Prairie Doc", a public television series that provides important health care information to South Dakotans.

February 2017 Michelle Baack, MD received a research grant from the Cooperative Neonatal Research Network (NRN).

January 2017 Dr. Michelle Baack published a paper titled "Breast milk DHA levels may increase after informing women: a community-based cohort study from South Dakota USA" in the International Breasefeeding Journal.  Docosahexaenoic acid (DHA) levels in breast milk were measured to determine if infants get an appropriate amount of DHA to support proper development.  Breastfeeding mothers at Sanford received testing and education on the importance of DNA and subsequently increased their DHA intake to retain recommended values in breast milk. 

December 2016 Dr. Baack met as part of the SD Medicaid Pharmacy and Therapeutics Committee which is a Governor appointed group that works with the Department of Social Services to ensure the needs of Medicaid recipients are met while addressing the high costs, clinical efficacy, safety and effectiveness of prescription drugs.

December 2016 Dr. Michelle Baack moderated a plenary session and judged research abstracts and posters at the annual meeting for the Midwest Society for Pediatric Research in Chicago, IL.

October 2016, Dr. Baack moderated a plenary session and judged abstracts and posters at the 2016 Midwest Society for Pediatric Research in Chicago, IL. She also attended the annual meeting for American Pediatric Society/Society for Pediatric Research while in Chicago.

September 2016,Dr. Kyle Sabey, a Pediatric Resident in the Baack laboratory, was awarded the Jack Metcoff Award for the best scientific oral presentation by a Resident/Fellow at the 2016 Midwest Society for Pediatric Research meeting in Chicago, IL. His presentation was entitled "The role of mitochondrial dynamism in developmentally programmed heart disease". https://www.aps-spr.org/Regions/MWSPR/awards/metcoff.asp

June 2016, Dr. Michelle Baack attended and presented at the 76th Scientific Session of the American Diabetes Association meeting in New Orleans, LA. Her talk was entitled “Maternal High-fat Diet Exacerbates Developmentally Programmed Cardiovascular Disease in Offspring of Diabetic Pregnancies through Impaired Cardiac Metabolism” as part of the Unraveling the Mysteries of Teratogenesis, Fetal Programming, and Adverse Pregnancy Outcomes Using Pioneering Technologies Session.

June 2016, Dr. Michelle Baack recently attended the NIDDK/NHLBI Mitochondrial Biology Symposium: Novel Roles of Mitochondrial in Health and Disease, Bethesda, MD. She presented on her research focused on “The Role of Bioenergetics and Mitochondrial Function in Developmentally Programmed Cardiac Disease in Offspring of Diabetic Pregnancy.”

May 2016, Dr. Michelle Baack recently attended the Pediatric Academic Society Meeting in Baltimore, MD. While there, she was inducted into the Society for Pediatric Research.  Additionally, she gave two poster presentations and a platform presentations on her work exploring how “Maternal Tobacco Smoke Exposure Impairs Placental Function and Induces Sex-Specific Alterations in Fetal Fatty Acids.” 

May 2016, Dr. Michelle Baack recently met in Pierre as part of a Governor’s Appointed Medicaid Advisory Committee.  Dr. Baack has served on this MAC since March 2014 and was appointed by Governor Daugaard.  The MAC – Medicaid Advisory Committee assists and advises the Department of Social Services in serving SD Medicaid recipients.  This month discussed Home and Community Based Services, Genetic Testing and Counseling, Budget, Applied Behavioral Services and expansion of Autism treatment and hear an update about Medicaid Expansion in our state. 

March 2016, Dr. Michelle Baack’s recent publication entitled “Maternal high-fat diet impairs cardiac function in offspring of diabetic pregnancy through metabolic stress and mitochondrial dysfunction” in the journal American Journal of Physiology - Heart and Circulatory Physiology has been nominated for distinction in scholarship for APS select  This is a collection of articles from the APS journals that showcases some of the best recently published articles in physiological research.

February 2016, Dr. Michelle Baack and her team have recently published a study entitled “Daily Enteral DHA Supplementation Alleviates Deficiency in Premature Infants” in the journal Lipids. This randomized, clinical trial demonstrates that premature infants receiving standard neonatal nutrition remained deficient in docosahexaenoic acid (DHA) throughout their hospitalization, but supplementation with 50mg/d of enteral DHA was well tolerated and alleviated deficiency. Coauthors on this publication included Michelle L Baack, Susan E Puumala, Stephen E Messier, Deborah K Pritchett, and William S Harris.

January 2016, Dr. Michelle Baack’s team recently had a publication in the American Journal of Physiology – Heart and Circulatory Physiology entitled “Maternal high-fat diet impairs cardiac function in offspring of diabetic pregnancy through metabolic stress and mitochondrial dysfunction.” Sanford co-authors on the publication include Dr. Kenney Mdaki, Tricia Larsen, Dr. Michelle Schimelpfenig, Angela Wachel and Sam Dooyema as well as USD medical student Lucinda J Weaver and Augustana undergraduate Eli J Louwagie. This study is the first to demonstrate that a maternal high-fat diet further impairs cardiac function in offspring of diabetic pregnancy through metabolic abnormalities, oxidative stress and mitochondrial dysfunction. Findings serve as a critical step in understanding the role of cellular bioenergetics in developmentally programmed cardiac disease.

January 2016, Dr. Michelle Baack will be an invited presenter at Perinatal Grand Rounds at the University of Alabama on January 20th. The title of her talk will be “Fats and the fetus: You are what your mother eats.”

November 2015, Dr. Michelle Baack attended the SDSMA executive council meeting, joint SDAHO and the policy council meetings in Pierre as a member of the executive board of the SDSMA.

November 2015, Dr. Kennedy Mdaki from the Baack lab represented Sanford Health at the American Heart Association Scientific Sessions meeting in Orlando FL where he received his AHA-Basic Cardiovascular Science (BCVS) Minority Travel Award.

November 2015, Dr. Michelle Baack was elected into the Society for Pediatric Research (SPR). Membership is highly selective and one must be nominated/sponsored for membership. The mission of SPR is to foster the research and career development of investigators engaged in creating new knowledge that advances the health and well-being of children and youth. Membership begins in 2016 and Dr. Baack will attend a new membership/awards banquet at the PAS meeting in Baltimore in May 2016.

November 2015, Dr. Michelle Baack was a co-author on a recent publication of a case report entitled “31-week Premature Male with Congenital Syphilis.” Other contributing authors from Sanford Health were Drs. Suzanne Reuter and David Munson. The article was published in the November issue of South Dakota Medicine.

October 2015, Dr. Michelle Baack attended the 14th biennial meeting of the diabetes in pregnancy study group of North America in Washington DC.

October 2015, Dr. Michelle Baack took a delegation of Sanford trainees to the Midwest Society of Pediatric Research (MWSPR) meeting in Kansas City. Sanford Research was represented by two platform presentations given by trainees in the Baack lab as well as two research poster presentations being given by trainees in the Weimer lab (Dr. Jill Weimer). Dr. Baack represents Sanford Health as an Executive Council member and session moderator for the MWSPR.