Lab News

April 2018 Sam Milanovich, Paola Vermeer,  and Alexei Savinov co-authored a research poster presented at the American Association for Cancer Research annual meeting in Chicago. This meeting covers the latest basic, translational, clinical and prevention-focused cancer research including areas such as early detection, cancer interception and survivorship. Dr. Milanovich presented the poster titled “Single nucleotide variations within and around microRNA-binding sites”. 

February 2018 Dr. Sam Milanovich attended the 2018 American Society of Hematology meeting in Atlanta, GA.  He met with industry and academic leaders to identify new collaborations and to learn about upcoming clinical trials that may benefit Sanford patients.

November 2017 Dr. Sam Milanovich received a $5,000 equipment grant from Alex’s Lemonade Stand Foundation (ALSF). Equipment will support genetic approaches used by the Milanovich laboratory to study chromatic changes in leukemia compare to normal blood development. ALSF is a national childhood cancer foundation dedicated to raising funds for research into new treatments and cures for all children battling cancer.

October 2017 Dr. Sam Milanovich gave an invited seminar at the American Society for Clinical Laboratory Science symposium in Sioux Falls, SD. "Laboratory tools in the diagnosis and management of acute leukemia: past, present, and future."

October 2017 Dr. Sam Milanovich was awarded the 2017 Augustana University Horizon Award, an honor that recognizes early career achievement by an alumnus within 15 years of graduation.

March 2017 Sam Milanovich, MD, co-authored a research article in Leukemia with Dr. Sridhar Rao of the BloodCenter of Wisconsin.These studies identify a novel epigenetic mechanism of disease in acute myelogenous leukemia (AML) patients with cohesion mutations. "The cohesion subunit of Rad21 is a negative regulator of hematopoietic self-renewal through epigenetic repression of Hoxa7 and Hoxa9.

November 2016, Dr. Milanovich was featured in a story by The Dickinson Press. The article highlights Dr. Milanovich's inspiration to research new diagnostic and therapeutic options for cancer patients.

August 2016, Dr. Milanovich co-authored a paper entitled "The cohesin subunit Rad21 is a negative regulator of hematopoeietic self-renewal through epigenetic repression of Hoxa7 and Hoxa9" in the journal Leukemia.

August 2016, Dr. Sam Milanovich was the recent coauthor on a study in the journal Leukemia that focuses on the role of the cohesin subunit Rad21 as a negative regulator of hematopoietic stem cell self-renewal through repression of two other factors, HoxA7 and HoxA9. Genetic studies have discovered that mutations in the cohesin complex, a cellular structure often found in Acute Myeloid Leukemia (a type of blood cancer). In this study, the describe for the first time the process and mechanisms behind how these mutations cause leukemia; identifying pathways that may help guide future treatment options for patients with cohesin-mutated leukemia.

August 2016, Dr. Sam Milanovich was recently invited to serve as an ad-hoc reviewer for the chapter “Hematopoiesis and Regenerative Medicine” in an e-book: Frontiers in Stem Cell and Regenerative Medicine Research.

June 2016, Dr. Sam Milanvich was a co-author on a recent publication in the journal Epigenetics and Chromatin entitled “The cohesin offloading factor Wapal is required for proper polycomb-mediated gene silencing."

April 2016, Dr. Sam Milanovich recently co-authored a research publication entitled “The cohesin offloading factor Wapal is required for proper polycomb-mediated gene silencing" in the journal Epigenetics and Chromatin

January 2016, Dr. Sam Milanovich appeared on a recent episode of the radio program “A Better You” on KSOO-AM 1140 to discuss his research on defining critical pathways in leukemia stem cells that could help improve understanding of leukemogenesis.

November 2015, Dr. Sam Milanovich recently had a “case quiz” published online as part of the American Society of Pediatric Hematology and Oncology, educational program. This “case quiz” can be found at:

September 2015, Sam Milanovich gave an invited seminar at Augustana College, Department of Biology entitled “Cancer Stem Cells: investigating the origins of leukemia”