Lab News

June 2018 Peter Vitiello gave an invited presentation to the Pulmonary Research Division at the University of Nebraska Medical Center. Dr. Vitiello spoke about ongoing work in his laboratory studying molecular regulation of perinatal lung development and pathogenesis of bronchopulmonary dysplasia. “Writing the redox code: thioredoxin signaling in development & disease”

June 2018 Brassica vegetables such as broccoli contain the anticancer chemical sulforaphane. Peter Vitiello assisted with the development of new anticancer chemicals by evaluating anticancer activities of newly synthesized chemicals based on the structure of sulforaphane. These findings were recently published in ChemMedChem. “Differentiating a Differentiating antiproliferative and chemopreventive modes of activity for electron-deficient aryl isothiocyanates against human MCF-7 cells”

May 2018 Peter Vitiello attended the annual meeting of the American Thoracic Society in San Diego, CA and presented a poster titled “Nuclear thioredoxin-1 potentiates inflammatory signaling and cell death during hyperoxic injury”.

April 2018 Bethany Mordhorst, postdoctoral fellow in the Vitiello lab, gave an invited presentation to the Department of Biomedical Engineering at the University of South Dakota.  Her talk titled "Pig as a biomedical model" was attended by faculty, staff, and students at the Graduate Education and Applied Research Center at USD.

April 2018 Peter Vitiello was one of twenty members of the Society for Redox Biology & Medicine (SfRBM) that participated in a strategic planning meeting in Chicago, IL.  SfRBM promotes research of free radical chemistry, redox biology and antioxidants in the context of human health and disease.

March 2018 Peter Vitiello received a grant from The Finish Line Foundation to study the influence of mitochondrial redox enyzmes on the pathogenesis of Friedreich's Ataxia, a rare inherited neuromuscular disease.

March 2018 Peter Vitiello gave an invited presentation to the Department of Biomedical Engineering at the University of South Dakota. His presentation, "Transgenic mouse models to understand redox signaling in health & disease” was attended by faculty, staff, and students at the Graduate Education and Applied Research Center at USD.

February 2018 Peter Vitiello was invited to participate in a workshop organized by Project Lead The Way (PLTW) in Indianapolis, IN. PLTW creates STEM learning experiences for K-12 students and Dr. Vitiello reviewed and discussed the PLTW biomedical sciences curriculum with teachers, undergraduate faculty and other health industry representatives.

February 2018 Peter Vitiello was recently elected to Chair of the STARBASE SD board.  STARBASE SD is funded by the Department of Defense and gives fifth grade students hands-on STEM learning experiences through interactive experiments.  Students attending any of the four STARBASE SD sites also have a unique opportunity to visit with military personnel and discover how they use STEM concepts, creativity and teamwork to solve problems.
 
February 2018 Peter Vitiello was accepted as a full member of the Perinatal Research Society (PRS).  PRS fosters scientific interchange between scientists of different disciplines who share common research interests in perinatal medicine and developmental biology.
 
January 2018 Dr. Peter Vitiello was invited to discuss his updates from his research program studying antioxidant enzymes in lung development and disease during perinatal grand rounds at the University of Alabama at Birmingham. “Writing the redox code: thioredoxin signaling in development & disease”
 

November 2017 The laboratory of Dr. Peter Vitiello attended the annual meeting of the Society for Redox Biology and Medicine (SfRBM) in Baltimore, MD. The laboratory presented new findings on the functions of an antioxidant enzyme in growth and metabolic signaling in a poster titled “Thioredoxin-1 activity is required for embryonic development and perinatal growth”. Dr. Vitiello also participated as an abstract reviewer, judge for young investigator awards and serves on the SfRBM council. The mission of SfRBM is to understand the advantageous and deleterious properties of free radicals and reactive oxygen and nitrogen species.

October 2017 Dr. Peter Vitiello was invited to join the Scientific Advisory Committee of the American Lung Association. This committee provides strategic advice on a range of subjects surrounding lung health and lung cancer.

August 2017 Dr. Peter Vitiello received a $2 million R01 grant from the NIH's National Heart, Lung, and Blood Institute for "Hyperoxic Modulation of Thioredoxin Signaling".

June 2017 Dr. Peter Vitiello was an invited speaker at the 2017 Central Region NIH Institutional Development Award (IDeA) Conference in Sioux Falls, SD. Dr. Vitiello presented results of a project he initiated as a Project Leader on the Sanford Research Center for Pediatric Research NIH CoBRE (an IDeA funded program). "Thioredoxin-dependent signaling during redox perturbation".

June 2017 Dr. Peter Vitiello attended a board meeting of the American Lung Association of the Upper Midwest (ALAUM) in Chicago, IL. The ALAUM is comprised of 10 states (IA, MN, ND, SD, NE, KS, IL, IN, WI, MO) and supports lung health for regional communities through lobbying activities, patient advocacy, clinical education, research support, and fundraising.

May 2017 Dr. Peter Vitiello published an education article in The American Biology Teacher describing a method that simulates enzyme-linked immunosorbent assay in the classroom. "Creating a reliable, cost-effective ELISA simulation".

April 2017, Peter Vitiello, PhD, was interviewed by South Dakota Public Radio to discuss health and disease applications using a genetically engineered mouse generated by his laboratory. http://listen.sdpb.org/programs/moment-innovation

March 2017, Peter Vitiello, PhD, attended a regional meeting of the Society for Redox Biology and Medicine hosted by the University of Alabama-Birmingham Center for Free Radical Biology in Birmingham, AL. The meeting focused on the influence of redox biology on human disease from scientists performing translational and clinical research.

February 2017, Peter Vitiello, PhD, was elected Vice President of the Board of Directors for South Dakota STARBASE. Four STARBASE sites in SD funded by the Department of Defense collectively serve over 4,000 5th grade students each year through a core curriculum that promotes problem-solving using physics, chemistry, engineering and technology. Concepts and principles are related to real-world scenarios through participation from military volunteers demonstrating how science and engineering principles support a variety of career applications.

January 2017: Dr. Peter Vitiello published a research article in Oxidative Medicine and Cellular Longevity titled “Detoxification of mitochondrial oxidants and apoptotic signaling are facilitated by thioredoxin-2 and peroxiredoxin-3 during hyperoxic injury” in PLoS ONE (PMID 28045936). Co-authors include Benjamin Forred, Darwin Daugaard, Brianna Titus, Ryan Wood, Dr. Miranda Floen, and Dr. Michelle Booze. https://www.ncbi.nlm.nih.gov/pubmed/?term=28045936

November 2016, Dr. Vitiello judged abstracts and posters while attending the 2016 meeting for the Society of Redox Biology & Medicine in San Francisco, CA.

November 2016, Dr. Vitiello gave an invited seminar entitled "Redox signaling during oxidative lung injury" to the Department of Physiology & Developmental Biology at Brigham Young University in Provo, UT.

November 2016: Dr. Peter Vitiello judged abstracts and posters while attending the annual meeting for the Society for Redox Biology & Medicine in San Francisco, CA.

October 2016: Dr. Peter Vitiello gave an invited seminar titled “Redox signaling during oxidative lung injury” to the Department of Physiology & Developmental Biology at Brigham Young University in Provo, UT.

September 2016, The Vitiello Lab published a study entitled "A novel mouse model for the identification of thioredoxin-1 protein interactions" in the journal Free Radical Biology & Medicine. http://www.ncbi.nlm.nih.gov/pubmed/27639450

September 2016: Dr. Peter Vitiello published a research article entitled “A novel mouse model for the identification of thioredoxin-1 protein interactions” in Free Radical Biology and Medicine (PMID 27639450). Co-authors include Drs. Michelle Booze and Jason Hansen (Brigham Young University). https://www.ncbi.nlm.nih.gov/pubmed/?term=27639450

August 2016: Dr. Peter Vitiello was recently interviewed on the local Sioux Falls radio program A Better You about his research on Sanford focused on how environmental toxins influence lung function and development and his passion for science education. Hear the complete interview here: https://soundcloud.com/sanford-health/a-better-you-82716-dr-peter-vititellocell-toxins-science-education

August 2016: Drs. Peter Vitiello and Michelle Baack published a research article entitled “Consequences of a maternal high-fat diet and late gestation diabetes on the developing rat lung” in PLoS One (PMID 27518105). Co-authors include Benjamin Forred, Tricia Larsen, Danielle Jensen, Angela Wachal, and Dr. Muhammad Khan. https://www.ncbi.nlm.nih.gov/pubmed/?term=27518105

July 2016, Dr. Peter Vitiello recently published a study from his laboratory entitled Identification of redox and glucose-dependent Txnip protein interactions” in the journal Oxidative Medicine and Cellular Longevity. Other Sanford Research co-authors on this study included Dr. Dae In Kim, Benjamin Forred, Dr. Kyle J. Roux, Skyla Neuharth, and Michael Amolins

June 2016: Dr. Peter Vitiello published a research article entitled “Identification of redox and glucose-dependent Txnip protein interactions” in Oxidative Medicine and Cellular Longevity (PMID 27437069). Co-authors include Benjamin Forred, Skyla Neuharth, Dr. Michael Amolins, Dr. Dae In Kim, and Dr. Kyle Roux. https://www.ncbi.nlm.nih.gov/pubmed/?term=27437069

June 2016: Dr. Peter Vitiello co-authored a research article with Dr. Seasson Vitiello from Augustana University in Biology Open entitled “Disruption of a cystine transporter downregulates expression of genes involved in sulfur regulation and cellular respiration” (PMID 27142334). https://www.ncbi.nlm.nih.gov/pubmed/?term=27142334

June 2016, Dr. Peter Vitiello was an invited lecturer as part of the international Redox Biology Graduate Course at The University of Nebraska-Lincoln. This annual course is sponsored by NIH COBRE-funded centers at The University of Nebraska-Lincoln and the Medical University of South Carolina, as well as Karolinska Institute

December 2015: Dr. Peter Vitiello published a research article titled “Evaluating the effectiveness of a laboratory-based professional development program for science educators” in Advances in Physiological Education. Co-authors include Drs. Michael Amolins, Cathy Ezrailson (University of South Dakota), David Pearce, and Amy Elliott. https://www.ncbi.nlm.nih.gov/pubmed/?term=26628658

November 2015, Dr. Peter Vitiello was invited to serve as the National Chair the Marketing Committee for the Society for Redox Biology & Medicine.

November 2015, Dr. Peter Vitiello and a postdoctoral fellow in his lab, Dr. Michelle Booze, presented two abstracts at the Redox Biology Symposium at University of Nebraska-Lincoln.

November 2015, Drs. Peter Vitiello and Michelle Booze attended the Society for Redox Biology & Medicine Conference in Boston, MA and presented one abstract.

October 2015: Dr. Peter Vitiello gave an invited seminar titled "Cysteine-based redox switches during lung development and hyperoxic injury" to the Free Radical and Radiation Biology Program at The University of Iowa in Iowa City, IA.

October 2015, Peter Vitiello of the CHRC serves as a Board Member for the American Lung Association of the Upper Midwest (ALA UM) and attended a regional boarding meeting in Indianapolis, IN. The ALA UM is a 10-state coalition promoting patient advocacy, clinical training, translational research, and philanthropy for the prevention and treatment of lung disease.

September 2015, Peter Vitiello gave an invited seminar at the Free Radical and Radiation Biology Program at The University of Iowa entitled "Cysteine-based redox switches during lung development and hyperoxic injury"

May 2015: Dr. Peter Vitiello, Dr. Michelle Booze, Benjamin Forred, Danielle Jensen, and Wendy Guevara presented research updates at the annual meeting for the American Thoracic Society in Denver, CO.

February 2015: Dr. Peter Vitiello gave an invited seminar to the Center for Free Radical Biology at The University of Alabama-Birmingham titled “Cysteine-based redox switches during lung development and hyperoxic injury” in Birmingham, AL.

February 2015: Dr. Peter Vitiello was invited to serve as a Board Member for the American Lung Association of the Upper Midwest (ALA UM). The ALA UM is a 10-state coalition promoting patient advocacy, clinical training, translational research, and philanthropy for the prevention and treatment of lung disease.

January 2015: Dr. Peter Vitiello gave an invited seminar to the Redox Biology Center at The University of Nebraska-Lincoln titled “Cysteine-based redox switches during lung development and hyperoxic injury” in Lincoln, NE.