Publications

Block RC, Harris WS, Reid KJ, Sands SA, Spertus JA. EPA and DHA in blood cell membranes from acute coronary syndrome patients and controls. Atherosclerosis. 197:821-828, 2008. PMID: 17875307 

Cohen BE, Garg SK, Ali S, Harris WS, Whooley MA. Red blood cell EPA and DHA concentrations are positively associated with Socioeconomic status in patients with established coronary artery disease: Data from the Heart and Soul Study. J Nutrition 138 :1135-1140, 2008.  PMID: 18492846
 
Aarsetoey H, Pönitz V, Nilsen OB, Grundt H, Harris W, Nilsen DWT. Low levels of cellular omega-3 increases the risk of ventricular fibrillation during the acute ischaemic phase of a myocardial infarction. Resuscitation 78:258-264, 2008. PMID: 18556107
 
Block RC, Harris WS, Pottala JV. Determinants of blood cell omega-3 fatty acid content. The Open Biomarkers J 1:1-6, 2008.  PMID: 19953197
 
Harris WS, Kris-Etherton PM, Harris KA. Intake of Long-Chain Omega-3 Fatty Acids Associated with Reduced Risk for Death from Coronary Heart Disease in Healthy Adults. Curr Athero Reports 10:503-9, 2008. (Oct) PMID: 18937898
 
Larson MK, Ashmore JH, Harris KA, Vogelaar JL, Pottala JV, Sprehe M, Harris WS. Effects of Omega-3 Acid Ethyl Esters and Aspirin, Alone and in Combination, on Platelet Function in Healthy Subjects. J Thromb Haemost 2008;100:634-41. (Oct). PMID: 18841286
 
Harris WS, Lemke SL, Hansen SN, Goldstein DA, DiRienzo MA, Su H, Nemeth MA, Taylor ML, Ahmed G, George C. Stearidonic Acid-Enriched Soybean Oil Increased the Omega-3 Index, an Emerging Cardiovascular Risk Marker. Lipids 2008;43:805-811. (Sept) PMID: 18683001
 
Amin AA, Menon RA, Reid KJ, Harris WS, Spertus JA Acute Coronary Syndrome Patients With Depression Have Low Blood Cell Membrane Omega-3 Fatty Acid Levels. Psychosom Med. 2008;70:856-62. (Oct). PMID: 18842751
 
Farzaneh-Far R, et al. Inverse association of erythrocyte n-3 fatty acid levels with inflammatory biomarkers in stable coronary artery disease: The Heart and Soul Study. Atherosclerosis 2009; 205:538-43 (Aug). PMID: 19185299.
 
Duda MK, O'shea KM, Tintinu A, Xu W, Khairallah RJ, Barrows BR, Chess DJ, Azimzadeh AM, Harris WS, Sharov VG, Sabbah HN, Stanley WC. Fish Oil, But Not Flaxseed Oil, Decreases Inflammation and Prevents Pressure Overload-Induced Cardiac Dysfunction. Cardiovasc Res. 2008;81:310-327. ( Nov) PMID: 19015135
 
Clarke R, Shipley M, Armitage J, Collins R, Harris WS. Plasma phospholipid fatty acids and coronary heart disease in older men: Whitehall study of London Civil Servants. Brit J Nutr 2009 102:279-284. PMID: 19105853.
 
Block RC, Harris WS, Reid KJ, Spertus JA. Omega-6 and trans fatty acids in blood cell membranes: a risk factor for acute coronary syndromes? Am Heart J. 2008;156:1117-23. (Dec) NIHMS75965. PMCID:  PMC2596644.
 
Lee JH, O’Keefe JH, Lavie CJ, Marchioli R, and Harris WS. Omega-3 Fatty Acids for Cardio-protection. Mayo Clinic Proc 2008;83:324-332.
 
Harris WS, Tighe AP, Miller M, Davidson M, Schaefer EJ. Omega-3 Fatty Acids and Coronary Heart Disease Risk: Clinical and Mechanistic Perspectives. Atherosclerosis 2008 ;197:12-24. PMID: 18160071
 
Harris WS, Von Schacky C. Omega-3 fatty acids, acute coronary syndromes and sudden cardiac death. Curr Cardiovasc Risk Rpt 2008;2:161-166..
 
Harris WS. The omega-3 index as a risk factor for coronary heart disease. Am J Clin Nutr 2008;87(suppl):1997S-2002S.
 
Ali S, Garg SK, Cohen BE, Bhave P, Harris WS, Whooley MA. Association between omega-3 fatty acids and depressive symptoms among patients with established coronary artery disease: Data from the Heart and Soul Study. Psychother Psychosom. 2009;78:125-127 (Feb). PMID: 19223688
 
Maki KC, Lubin BC, Reeves MS, Dicklin MR, Harris WS. Prescription omega-3 acid ethyl esters and simvastatin 20 and 80 mg: effects in mixed dyslipidemia. J Clin Lipidol 2009;3:33-38 (Feb). 
 
Harris WS, Jacobson TA. Omega-3 Fatty Acids. In: Clinical Lipidology: A Companion to Braunwald’s Heart Disease. Ed. CM Ballantyne. Saunders Elsevier, Philadelphia; 2009; pp.326-338.
 
Harris WS, Mozaffarian D, Rimm E, Kris-Etherton PM, Rudel LL, Appel LJ, Engler MM, Engler MB, Sacks F. Omega-6 Fatty Acids and Risk for Cardiovascular Disease. A Science Advisory from the American Heart Association Nutrition Committee. Circulation 2009;119:902-907. PMID: 19171857
 
Harris WS, Mozaffarian D, Lefevre M, Toner CD, Colombo J, Cunnane SC, Holden JM, Klurfeld DM, Morris MC, Whelan J. Towards Establishing Dietary Reference Intakes for Eicosapentaenoic and Docosahexaenoic Acids. J Nutrition 2009;139:804S-819S. PMID: 19244379
 
Brownawell AM, Harris WS, Hibbeln JR, Klurfeld DM, Newton I, Yates A. Assessing the environment for regulatory change for EPA and DHA nutrition labeling. Nutr Rev 2009;67:391-397. PMID: 19566599
 
Harris WS. The Omega-3 Index: From biomarker to risk marker to risk factor. Curr Athero Rept 2009;11:411-417. Nov; PMID: 19852881
 
Lee JH, O'Keefe JH, Lavie CJ, Harris WS. Omega-3 fatty acids: cardiovascular benefits, sources and sustainability. Nat Rev Cardiol. 2009 Oct 27. PMID: 19859067.
 
Kris-Etherton PM, Fleming J, Harris WS. The debate about n-6 polyunsaturated fatty acid recommendations for cardiovascular health. J Am Diet Assn 2010;10:201-204. doi: 10.1016/j.jada.2009.12.006. PMID: 20102846
 
Shearer GC, Pottala JV, Spertus JA, Harris WS (2009) Red Blood Cell Fatty Acid Patterns and Acute Coronary Syndrome. PLoS ONE 4(5): e5444. doi:10.1371/journal.pone.0005444.  PMID: 19185299
 
Shearer GC, Harris WS, Pedersen TL, Newman JW. Detection of omega-3 oxylipins in human plasma and response to treatment with omega-3 acid ethyl esters. J Lipid Res. 2009;51:1074-1081 PMID: 19671931.
 
Aarsetoey H, Volker P, Grundt H, Staines H, Harris WS, Nilsen DWT. (n-3) fatty acid content of red blood cells does not predict risk of future cardiovascular events following an acute coronary syndrome. J Nutr 2009;139:1–7. PMID: 19158216
 
Park Y, Harris WS. Dose-Dependent Effects of n-3 Polyunsaturated Fatty Acids on Platelet Activation in Mildly Hypertriglyceridemic Subjects. J Med Food. 2009,12:809-813. doi:10.1089/jmf.2008.1097. August. PMID: 19735181
 
Park Y, Harris WS. Dose-Response of n-3 Polyunsaturated Fatty Acids on Lipid Profile and Tolerability in Mildly Hypertriglyceridemic Subjects. J Med Food. 2009,12:803-808. doi:10.1089/jmf.2008.1250. August. PMID: 19735180
 
Harris WS, Thomas RM. Biological Variability of Blood Omega-3 Biomarkers. Clin Biochem 2010;43:338–340.  PMID: 19733159
 
Carney RM, Freeland KE, Rubin EH, Rich MW, Steinmeyer BC, Harris WS. Omega-3 augmentation of sertraline in the treatment of depression in patients with coronary heart disease: a randomized controlled trial. JAMA 2009; 302:1651-1657 (October). PMID: 19843899
 
Shearer GS, Chen J, Chen Y, Harris WS. Myocardial infarction does not affect erythrocyte fatty acid profiles in rats. Prost Leuko Ess Fatty Acids 2009;81:411-416 (Sept).  PMID: 19775878
 
Farzaneh-Far R, Lin J, Epel ES, Harris WS, Blackburn EH, Whooley MA. Association of marine omega-3 fatty acid levels with telomeric aging in patients with coronary heart disease. JAMA 2010;303(3):250-257. PMID: 20085953
 
Billman GE, Nishijima Y, Belevych AE, Terentyev D, Xu1 Y, Haizlip1 KM, Monasky1 MM, Hiranandani1 N, Harris WS, Gyorke S, Carnes CA, Janssen PML. Effects of Dietary Omega-3 Fatty Acids on Ventricular Function in Dogs with Healed Myocardial Infarctions: In Vivo and In Vitro Studies. Am J Physiol Heart Circ Physiol. Jan 22 2010 PMID: 20097770
 
Block RC, Duff R, Lawrence P, Kakinami L, Brenna JT, Shearer GC, Meednu N, Mousa S, Friedman A, Harris WS, Larson M, Georas S.The Effects of EPA, DHA, and Aspirin Ingestion on Plasma Lysophospholipids and Autotaxin. Prostagl Leukot Essent Fatty Acids. 2010 Jan 25. [Epub ahead of print] PMID: 20106646
 
Harris WS. Omega-3 and Omega-6 Fatty Acids: Partners in Prevention. Curr Opin Clin Nutr Metabol Care. 2010;13:125-129. (March) PMID: 20145438
 
Robinson JG, Ijioma N, Harris W. Omega-3 fatty acids and cognitive function in women. Women’s Health (Lond Engl). 2010 Jan;6(1):119-34. PMID: 20088735.
 
Harris WS. The Omega-3 Index: Clinical Utility for Therapeutic Intervention. Curr Cardiol Rep. 2010 (Sept). 12:503–508. PubMed PMID: 20809235.
 
Ebbesson SOE, Devereux RB, Cole S, Ebbesson LOE, Fabsitz RR, Haack K, Harris WS, Howard WH, Laston S, Lopez-Alvarenga JC, MacCluer JW, Okin PM, Tejero E, Voruganti VS, Wenger CR, Howard BV, Comuzzie AG. Heart Rate is Associated with Red Blood Cell Fatty Acid Concentration: the GOCADAN Study. Am Heart J, 2010;159:1020-1025. PMID: 20569715
Pottala JV, Garg S, Cohen BE, Whooley MA, Harris WS. Blood EPA and DHA Independently Predict All-Cause Mortality in Patients with Stable Coronary Heart Disease. The Heart and Soul Study. Circ:Qual Outcomes 2010;3 406-412. PMID: 20551373
 
Carney RM, Freedland KE, Stein PK, Steinmeyer BC, Harris WS, Rubin EH, Krone RJ, Rich MW. The Effect of Omega-3 Fatty Acids on Heart Rate Variability in Depressed Patients With Coronary Heart Disease. Psychosomat Med 2010;72(8):748-54. PMID: 20716712
 
Ebbesson SO, Tejero ME, López-Alvarenga JC, Harris WS, Ebbesson LO, Devereux RB, MacCluer JW, Wenger C, Laston S, Fabsitz RR, Howard BV, Comuzzie AG. Individual saturated fatty acids are associated with different components of insulin resistance and glucose metabolism: the GOCADAN study. Int J Circumpolar Health. 2010;69:344-51. PMID: 20719107.
 
Lemke SL, Vicini JL, Su H, Goldstein DA, Nemeth MA, Krul ES, Harris WS.  Dietary intake of stearidonic acid enriched soybean oil increases the omega-3 index: randomized, double-blind clinical study of efficacy and safety. Am J Clin Nutr. 2010;92(4):766-75. PMID: 20739419. 
 
Chen J, Shearer GS, Chen Q, Healy CL, Beyer AJ, Nareddy VB, Gerdes AM, Harris WS, O’Connell TD, Wang D. Omega-3 fatty acids prevent pressure overload-induced cardiac fibrosis through activation of cGMP/PKG signaling in cardiac fibroblasts. Circulation 2011;123:584-93. PMID: 21282499.
 
Yang R, Harris WS, Vernon K, Thomas AM, Qureshi N, Morrison DC, Van Way CW 3rd. Pre-feeding with omega-3 fatty acids suppresses inflammation following hemorrhagic shock.  J Parenter Enteral Nutr. 2010 Sep-Oct;34(5):496-502.  PMID: 20852177
 
Skulas-Ray AC, Kris-Etherton PM, Harris WS, Vanden Heuvel JP, Wagner PR, West SG. Dose response effects of omega-3 fatty acids on triglycerides, inflammation, and endothelial function in healthy people with moderate hypertriglyceridemia. Am J Clin Nutr. 2011;93:243-52. PMID:21159789.
 
Larson MK, Shearer GC, Ashmore JH, Anderson-Daniels JM, Graslie EL, Tholen JT, Vogelaar JL, Korth AJ, Nareddy V, Sprehe M, Harris WS. Omega-3 fatty acids modulate collagen signaling in human platelets. Prostaglandins Leukot Essent Fatty Acids. 2011;84:93-8. PMID: 21177087.
 
Hu S, Shearer GC, Steffes MW, Harris WS, Bostom AG. Once-daily extended-release niacin lowers serum phosphorus concentrations in patients with metabolic syndrome dyslipidemia. Am J Kidney Dis. 2011;57:181-2. PMID: 20888102.
 
Aarsetøy H, Aarsetøy R, Lindner T, Staines H, Harris WS, Nilsen DWT. Low Levels of the Omega-3 Index are Associated with Sudden Cardiac Arrest and Remain Stable in Survivors in the Subacute Phase. Lipids 2011;46:151-61. PMID:21234696
 
Moyers B, Farzaneh-Far R, Harris WS, Garg S, Na B, Whooley MA. Relation of Whole Blood n-3 Fatty Acid Levels to Exercise Parameters in Patients With Stable Coronary Artery Disease (from the Heart and Soul Study). Am J Cardiol. 2011;107:1149-54. PMID:21306696
 
Sala-Vila A, Harris WS, Cofán M, Pérez-Heras AM, Pintó X, Lamuela-Raventós RM, Covas M-I, Estruch R, Ros E. Determinants of the omega-3 index in a Mediterranean population at increased risk for coronary heart disease. Brit J Nutr 2011; epub before print March 30. PMID:21450116
 
Billman GE, Harris WS. Effect of Dietary Omega-3 Fatty Acids on the Heart Rate and the Heart Rate Variability Response to Myocardial Ischemia or Submaximal Exercise. Am J Physiol Heart Circ Physiol. 2011 Apr 1. [Epub ahead of print]. PMID:21460198 
 
Salisbury AC, Amin AP, Harris WS, Chan PS, Gosch KL, Rich MW, O'Keefe JH Jr, Spertus JA. Predictors of omega-3 index in patients with acute myocardial infarction. Mayo Clin Proc. 2011 Jul;86(7):626-32.
 
Ladesich JB, Pottala JV, Romaker A, Harris WS. Membrane Level of Omega-3 Docosahexaenoic Acid Is Associated with Severity of Obstructive Sleep Apnea. J Clin Sleep Med 2011; 7:391-396.