Liang Lab

Research in Liang laboratory is devoted to understanding the molecular events and intracellular signaling mechanisms that underlie heart failure, a clinical syndrome that occurs in virtually all cardiovascular diseases and is one of the major causes of mortality in human population. Using an approach that combines cell culture system and genetic altered animal models, we are currently conducting research in three major areas:

  • Explore mechanisms of myocardial protection by caloric restriction and develop drugs that mimic the beneficial effects of caloric restriction.
  • Investigate why diabetic patients and animals are predisposed to heart failure and suggest mechanism-based approach to reduce the susceptibility. 
  • Investigate why the anti-cancer drug doxorubicin can cause heart failure and how myocardial homeostasis can be restored by coordinately promoting survival mechanisms and blocking cell death pathways.

 

Contact Information for Liang Lab:

Qiangrong Liang, MD, PhD

Scientist, Cardiovascular Health Research Center

Sanford Research/USD
2301 E. 60th Street N
Sioux Falls, SD 57104
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Phone:605-312-6304

qiangrong.liang@sanfordhealth.org