Wright Lab

The focus of the Wright lab is the development of a new alpha1-AR antagonist for the treatment of hypertension and benign prostate hyperplasia. Clinical trials have shown that blockade of alpha-1 adrenergic receptor activation can lead to increased incidence of heart failure in patients with hypertension and/or benign prostate hyperplasia.  Current projects include localization of alpha1-AR subtypes in vascular and prostate smooth muscle cells versus cardiac myocytes and the signal transduction differences between alpha1-AR at the plasma membrane and a1-AR inside the cell.

 

Contact Information for Wright Lab:

Casey Wright, PhD
Assistant Scientist, Cardiovascular Health Research Center

Sanford Research/USD
2301 E. 60th Street N
Sioux Falls, SD 57104
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Phone: 605-312-6308