Publications

PEER REVIEWED PUBLICATIONS:

Milone M, Klassen BT, Landsverk ML, Haas RH, Wong LJ. (2013) Orthostatic Tremor, Progressive External Ophthalmoplegia, and Twinkle. JAMA Neurol. Nov;70(11):1429-31

Tang S, Wang J, Zhang VW, Li FY, Landsverk M, Cui H, Truong CK, Wang G, Chen LC, Graham B, Scaglia F, Schmitt ES, Craigen WJ, Wong LJ. (2013). Transition to next generation analysis of the whole mitochondrial genome: a summary of molecular defects. Hum Mutat. Jun;34(6):882-93.

Cui H, Li F, Chen D, Wang G, Truong CK, Enns GM, Graham B, Milone M, Landsverk ML, Wang J, Zhang W, Wong LJ. (2013) Comprehensive next-generation sequence analyses of the entire mitochondrial genome reveal new insights into the molecular diagnosis of mitochondrial DNA disorders. Genet Med. May;15(5):388-94.

Landsverk ML, Douglas GV, Tang S, Zhang VW, Wang G, Wang J, Wong LJ (2012) Diagnostic Approaches to Apparent Homozygosity. Genet Med. Oct;14(10):877-82.

Wang J, Schmitt ES, Landsverk ML, Zhang VW, Li FY, Graham BH, Craigen WJ, Wong LJ. (2012) An integrated approach for classifying mitochondrial DNA variants: one clinical diagnostic laboratory's experience.
Genet Med. Jun;14(6):620-6.

Stieren ES, El Ayadi A, Xiao Y, Siller E, Landsverk ML, Oberhauser AF, Barral JM, Boehning D. (2011) Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein. J Biol Chem. Oct 14;286(41):35689-98.

Landsverk ML, Wang J, Schmitt ES, Pursley AN, Wong LJ. (2011) Utilization of Targeted Array Comparative Genomic Hybridization, MitoMet®, in Prenatal Diagnosis of Metabolic Disorders. Mol Genet Metab. Jun;103(2):148-52.

Fruhman G,* Landsverk ML,* Lotze TE, Hunter JV, Wangler MF, Adesina AM, Wong LJ, Scaglia F. (2011) Atypical presentation of Leigh syndrome associated with a Leber hereditary optic neuropathy primary mitochondrial DNA mutation. Mol Genet Metab. Jun;103(2):153-60. *co-first authors

Sadikovic B, Wang J, El-Hattab A, Landsverk M, Douglas G, Brundage EK, Craigen WJ, Schmitt ES, Wong LJ. (2010)
Sequence homology at the breakpoint and clinical phenotype of mitochondrial DNA deletion syndromes. PLoS One. Dec 20;5(12):e15687.

Landsverk ML, * Weiser DC, * Hannibal MC, Kimelman D. (2010) Alternative splicing of sept9a and sept9b in zebrafish produces multiple mRNA transcripts expressed throughout development.PLoS One. May 19;5(5):e10712. *co-first authors

Collie AM, * Landsverk ML, * Ruzzo E, Mefford HC, Buysse K, Adkins JR, Knutzen DM, Barnett K, Brown RH Jr, Parry GJ, Yum SW, Simpson DA, Olney RK, Chinnery PF, Eichler EE, Chance PF, Hannibal MC. (2010) Non-recurrent SEPT9 duplications cause hereditary neuralgic amyotrophy. J Med Genet. 47(9):601-7. Epub 2009 Nov 25. *co-first authors

Landsverk ML,* Ruzzo EK,* Mefford HC, Buysse H, Buchan JG, Petty EM, Peterson EA, Eichler EE, Knutzen DM, Barnett K, Bedford HM, Bird TD, Chance PF, Hannibal MC. (2009) Duplication within the SEPT9 gene associated with a founder effect in North American families with Hereditary Neuralgic Amyotrophy. Hum Mol Genet. 18(7):1200-8. *co-first authors

Hannibal MC, Ruzzo EK, Miller LM, Betz B, Buchan JG, Knutzen DM, Barnett K, Landsverk ML, Andermann E, Brice A, LeGuern E, Bedford HM, Worrall BB, Lovitt S, Appel SH, Bird TD, Chance PF. (2009) SEPT9 Gene Sequencing Analysis Reveals Recurrent Mutations in Hereditary Neuralgic Amyotrophy. Neurology. 72(20):1755-9.

Steinmann C, Landsverk ML, Barral JM, Boehning D. (2008). Requirement of Inositol 1,4,5-Trisphosphate Receptors for Tumor-mediated Lymphocyte Apoptosis. J Biol Chem. 283:13506-9. Accelerated Communication.

Landsverk ML,* Li S,* Hutagalung AH, Najafov A, Hoppe T, Epstein HF. (2007) Chaperone-mediated Regulation of Myosin Assembly and Turnover in Caenorhabditis elegans. J. Cell Biol. 177: 205-10. Cover: Chaperoning Muscle-Builders. Outlook: The critical chaperone balance, 177:185. *co-first authors.

Miller RK, Qadota H, Landsverk ML, Mercer KB, Epstein HF, Benian GM (2006) UNC-98 is a molecular bridge between muscle focal adhesions and thick filaments in C. elegans. J. Cell Biol. 175: 853-859.

Landsverk ML, and Epstein HF. (2005) Genetic analysis of myosin II assembly and organization in model organisms. Cell Mol. Life Sci. 62: 2270-82.

Price MP, Landsverk ML, Barral JM, Epstein HF. (2002) Two mammalian UNC-45 isoforms are related to distinct cytoskeletal and muscle-specific functions. J. Cell Sci. Nov 115: 4013-4023.

Hutagalung AH, Landsverk ML, Price MG, Epstein HF. (2002) The UCS family of myosin chaperones. J Cell Sci. Nov 115: 3983-90.

BOOK CHAPTERS:

Landsverk ML and Wong LJ (2013) Clinical Molecular Diagnostic Techniques: A Brief Review. In Next Generation Sequencing; Translation to Clinical Diagnostics (pp.19-36) New York: Springer.

Wang J, and Landsverk ML (2013) Algorithms and Guidelines for Interpretation of DNA Variants. In Next Generation Sequencing; Translation to Clinical Diagnostics (pp.97-112) New York: Springer.

Landsverk ML, Cornwell ME, Palculict ME. (2012) Sequence analysis of the whole mitochondrial genome and nuclear genes causing mitochondrial disorders. Methods Mol Biol. 837:281-300.