Lab Members

Dave Pearce, PhD :: Scientist & Executive Vice President; Sanford Research

I am fortunate to guide the following individuals in our pursuit of understanding the molecular basis of lysosomal storage disorders such as Batten disease.

Rosanna Beraldi :: Staff Scientist

I am currently working on developing a pig animal model for neurological diseases such as Ataxia telangiectasia and Batten disease. I love to work with large animal models of neurological diseases and I hope that through them we can easily elucidate the underlying mechanism of human neurological dysfunctions and maybe generate therapeutic protocols to halt or reverse the pathological conditions.

Ryan Geraets:: MD/PhD Program, Sanford School of Medicine 

My area of focus within Dr. Pearce’s lab will primarily consist of discovering potential pharmacotherapeutic options for various forms of Neuronal Ceroid Lipofuscinoses (NCL). To do this, I will be using a variety of NCL models and laboratory technics.

 Attila Kovács

Attila Kovács :: Assistant Research Scientist

I work on several projects including: a) behavioral characterization of new mouse models of infantile, late infantile and juvenile Batten disease; b) testing various pharmacotherapeutic approaches in mouse models of Batten disease; and c) electrophysiological characterization of abnormalities in neurotransmission in mouse models of Batten disease using acutely isolated brain slices and a microelectrode array system. The aim of the latter project is to better understand the pathomechanism of the disease and to identify new therapeutic targets.

Logan Langin

Logan Langin :: Senior Labratory Technician

I am responsible for many of the operational and logistical needs of the Pearce lab, supervision and management of the animal colonies, as well as oversight of various collaborations with other researchers inside and outside of Sanford Research. My current project includes behavioral, histological, and molecular characterization of a novel mouse model for JNCL with hopes for future therapeutic treatment study and development.