Jill Weimer Lab

Weimer Lab

Primary research focus

Jill Weimer, PhD

Research in the Weimer Lab is focused on understanding the mechanisms underlying the mammalian central nervous system development. Dr. Weimer and the team hope to gain a better understanding of the mechanism required for the polarized spatial restriction, advancing our knowledge of neural stem cell biology and aiding in the future treatment of neural developmental disorders and neurodegenerative diseases.
  • Director and Scientist in the Children's Health Research Center
  • Associate professor for the Department of Pediatrics at the Sanford School of Medicine at the University of South Dakota
  • Bachelor of Science and doctorate in neuroscience at the University of Rochester, Rochester, NY
  • Postdoctoral fellowship in The Neuroscience Center at the University of North Carolina, Chapel Hill

Sanford Research - Weimer Lab

Behind the research

Dr. Weimer’s research team is interested in understanding mechanisms of polarized signaling that regulate the proliferation and placement of neuronal progenitors in the developing cerebral cortex and whether similar cellular processes assist in neurons faithful ability to acquire unique yet often complex polarized morphologies.

To approach these questions, we combine mouse genetics, in uterus embryonic manipulation and ex vivo preparations (e.g. hippocampal dissociated neuronal culture, organotypic brain slice culture) with various assays including two-photon/confocal laser scanning microscopy imaging. Employing these techniques, we hope to gain better understanding of the mechanism required for the polarized spatial restriction of critical signaling complexes in neural progenitors of the developing cerebral cortex, advancing our knowledge of neural stem cell biology and aiding in the future treatment of neural developmental disorders and neurodegenerative diseases.

Resources Positions Available
Access Dr. Weimer's publications here. There are zero open positions within the Weimer lab at this time.
Meet members of the Weimer lab here.
Find links and tools here.

 

Lab Projects Contact Information
CRMP2: A key regulatory mediator of neuropsychiatric disorders Telephone: (605) 312-6407
Email: jill.weimer@sanfordhealth.org
MARCKS-associated signaling complexes in cortical develop
Rho GTPase Signaling in the Developing Cerebral Cortex

 

Weimer Lab in the Press
Sanfordhealth.org: Weimer to lead collaborative team in development of novel animal model of neurofibromatosis
KELOLAND.com: Weimer to lead collaborative team in development of novel animal model of neurofibromatosis
Argus Leader: Weimer to lead collaborative team in development of novel animal model of neurofibromatosis
Weimer recognized as a Sioux Falls Mover and Shaker
Dr. Jill Weimer appears on an episode of the national televised program “The Doctors” to discuss her work on Batten disease and with The Charlotte and Gwenyth Gray Foundation
Weimer team secures nearly $440,000 in funding to support Batten disease research
Dr. Jill Weimer appears on local TV program to discuss ongoing Batten’s research
Sanford Research's Weimer Secures NIH Grant
Press Archive

 

Lab News

May 2016, USD graduate student Jon Brudvig has won a 2016 National Defense Science and Engineering Graduate (NDSEG) Fellowship. Jon is a second year PhD student in the Basic Biomedical Sciences program. He is completing his dissertation research in the Weimer Lab at Sanford Research, studying the role of cell polarity proteins in development of the cerebral cortex. The NDSEG is a highly competitive predoctoral fellowship funded by the Department of Defense, and supports individuals who have demonstrated the ability and special aptitude for advanced training in science and engineering.

May 2016, Dr. Jill Weimer was recently elected to the Alumnae Council for the School of Medicine and Dentistry of the University of Rochester in Rochester NY. Dr. Weimer received her BA, MS, and PhD from the University of Rochester and was the very first graduate student member appointed to the council while she was at student at the UR.

April 2016, Jon Brudvig, a graduate student in the Weimer lab, has received a travel award from the Center for Brain and Behavior Research (CBBRe) at USD to attend the 2016 Neural Development Gordon Research Conference in Newport, RI. Jon has also been selected to attend a pre- "Neural Development" Gordon Research Seminar (GRS) for graduate and postdoctoral trainees. Jon is a second year PhD candidate in the Basic Biomedical Science Program at USD.

March 2016, Rachel Laufmann, a senior at USD and full-time technician in the Weimer lab, has been awarded the 2016 Undergraduate Research Excellence Award from the University of South Dakota. This prestigious award recognizes 3+ years’ of research that Rachel conducted both as an REU/SPUR scholar and as a part of her undergraduate honors thesis. The award includes a grant of $500, a featured month in the USD 2017 Office of Research and Sponsored Programs calendar, and a framed citation for her accomplishments.

March 2016, Dr. Jill Weimer gave an invited lecture at the 2016 American Society for Neurochemistry in Denver March 19-23rd. Dr. Weimer’s presentation will be a part of a special panel entitled “Old Friends and New Roles: Brain Patterning and Signal Transduction.” The goal of the American Society for Neurochemistry is to advance and promote the science of neurochemistry and related neurosciences and to increase and enhance neurochemical knowledge.

 News Archive