Publications

Peer-reviewed Papers in Scientific Journals

Harris WS, Marai L, Myher JJ, Subbiah MTR. Bile Acid Ethyl Esters: their infrequent formation during routine bile acid analysis and identification by gas chromatography and mass spectrometry. J Chromatog 131:437-441, 1977. PMID: 16027

Horner MR, Harris WS, Brownlee BJ, Goldstein RS, Taylor AK. Anthropometric and Dietary Study of Miskito Indian children in rural Nicaragua. Ecology of Food and Nutrition 6:137-146, 1977. Not available.
 
Harris WS, Kottke BA, Subbiah MTR. Bile acid metabolism in ascorbic acid-deficient guinea pigs. Am J Clin Nutr 32:1837-1841, 1979. PMID: 474473
 
Harris WS, Connor WE. The effects of salmon oil upon plasma lipids, lipoproteins and triglyceride clearance. Trans Assoc Am Physicians 43:148-155, 1980. PMID: 7195627
 
Goodnight SH, Harris WS, Connor WE. The effects of dietary omega-3 fatty acids on platelet composition and function in man: a prospective, controlled study, Blood 58:880-885, 1981. PMID: 7295999
 
Harris WS, Connor WE, Goodnight SH. Dietary fish oils, plasma lipids and platelets in man. Prog Lipid Res 20:75-79, 1981. PMID: 7342128
 
Goodnight SH, Harris WS, Connor WE and Illingworth DR. Polyunsaturated Fatty Acids, Hyperlipidemia and Thrombosis. Arteriosclerosis 2:87-113, 1982. PMID: 7039582
 
Harris WS, Connor WE, McMurry MP. The comparative reductions of the plasma lipids and lipoproteins by dietary polyunsaturated fats: salmon oil versus vegetable oils. Metabolism 32:179-184, 1983. PMID: 6827988
Harris WS, Connor WE, Lindsey S. Will dietary w-3 fatty acids change the composition of human milk? Am J Clin Nutr 40:780-785, 1984. PMID: 6237575
 
Illingworth DR, Harris WS, Connor WE. Inhibition of low density lipoprotein synthesis by dietary omega-3 fatty acids in humans. Arteriosclerosis 4:270-275, 1984. PMID: 6712540
 
Harris WS, Connor WE, Inkeles SB, Illingworth DR. Dietary Omega-3 fatty acids prevent carbohydrate-induced hypertriglyceridemia. Metabolism 33:1016-1019, 1984. PMID: 6493044
 
Phillipson BE, Rothrock DR, Connor WE, Harris WS, Illingworth DR. Reduction of plasma lipids, lipoproteins and apoproteins by dietary fish oils in patients with hypertriglyceridemia. N Eng J Med 312:1210-1216, 1985. PMID: 3990714
 
Zucker ML, Bilyeu DS, Helmkamp GM, Harris WS, Dujovne CA. Effects of dietary fish oil on platelet function and plasma lipids in hyperlipoproteinemic and normal subjects. Atherosclerosis 73:13-22, 1988. PMID: 3178928
 
Harris WS, Dujovne CA, Zucker ML, Johnson BE. Effects of a low saturated fat, low cholesterol fish oil supplement in hypertriglyceridemic patients - A placebo-controlled trial. Ann Intern Med 109:465-470, 1988. PMID: 3166357
 
Harris WS, Zucker ML, Dujovne CA. Omega-3 fatty acids in hypertriglyceridemic patients: triglycerides vs methyl esters. Am J Clin Nutr 48:992-997, 1988. PMID: 3421209
 
Harris WS, Connor WE, Alam N, Illingworth DR. Reduction of postprandial triglyceridemia in humans by dietary omega-3 fatty acids. J Lipid Res 29:1451-1460, 1988. PMID: 3241121
 
Harris WS. Fish oils and plasma lipid and lipoprotein metabolism in humans: A critical review. J Lipid Res 30:785-807, 1989 PMID: 2677200
 
Illingworth DR, Connor WE, Hatcher LF, Harris WS. Hypolipidemic effects of n-3 fatty acids in primary hyperlipoproteinemia. J Intern Med (formerly Acta Med Scand), 225:91-7, 1989. PMID: 2650700
 
Vacek JL, Harris WS, Haffey K. Short-term effects of omega-3 fatty acids on exercise stress test parameters, angina and lipoproteins. Biomed Pharmacotherap 43:375-380, 1989. PMID: 2551411
 
Harris WS, Rothrock DW, Fanning A, Inkeles, SB, Goodnight SH, Jr, Illingworth DR, Connor WE. Fish oils in hypertriglyceridemia: A dose-response study. Am J Clin Nutr 51:399-406, 1990. PMID: 2309646
 
Harris WS, Silveira S, Dujovne CA. The combined effects of omega-3 fatty acids and aspirin on hemostatic parameters in man. Thromb Res 57:517-526, 1990. PMID: 2109371
 
Harris WS, Rayford A. LCAT inhibitors interfere with the enzymatic determination of cholesterol and triglycerides. Lipids 25:341-343, 1990. PMID: 2164127
 
Inagaki M, Harris WS. Changes in lipoprotein composition in hypertriglyceridemic patients taking cholesterol-free fish oil supplements. Atherosclerosis 82:237-246, 1990. PMID: 2375788
 
Harris WS, Connor WE, Illingworth DR, Rothrock DW, Foster DM. Effects of fish oil on VLDL triglyceride kinetics in humans. J Lipid Res 31:1549-1558, 1990. PMID: 2246608
 
Harris WS, Dujovne CA, von Bergmann K, Neal J, Akester J, Windsor S, Green D, Look Z. Effects of the ACAT inhibitor CL 277,082 on cholesterol metabolism in humans. Clin Pharmacol Therap 48:189-194, 1990. PMID: 2199133
 
Harris WS, Windsor SL, Dujovne CA. Effects of four doses of n-3 fatty acids given to hyperlipidemic patients for six months. J Am Coll Nutr 10:220-227, 1991. PMID: 1832701
 
Sztern MI, Harris WS. Short-term effects of fish oil on human plasma lipid levels. J Nutr Biochem 2:255-259, 1991. Not available.
 
Harris WS, Windsor SL. N-3 fatty acid supplements reduce chylomicron levels in healthy volunteers. J Applied Nutr 43:5-15, 1991. Not available.
 
Harris WS, Hurwitz A, Stagel WW, Burns TS, Tschanz C. Evaluation of clinical and biochemical parameters after short-term consumption of microparticulated protein fat substitute (Simplesse®) in a frozen dessert. Asia Pacific J Clin Nutr 1:81-87, 1992. Not available.
 
Harris, WS. The prevention of atherosclerosis with antioxidants. Clin Cardiol 15:636-640, 1992. PMID: 1395197
Harris WS, Muzio F. Fish oil reduces postprandial triglyceride concentrations without accelerating lipid-emulsion removal rates. Am J Clin Nutr 58:68-74, 1993. PMID: 8317392
 
Hunninghake DB, Stein EA, Dujovne CA, Harris WS, Feldman EB, Miller VT, Tobert JA, Laskarzewski PM, et al. The efficacy of intensive dietary therapy alone or combined with lovastatin in outpatients with hypercholesterolemia. N Engl J Med 328:1213-1219, 1993. PMID: 8464431
 
Phelps S and Harris WS. Garlic Supplementation and Lipoprotein Oxidation Susceptibility. Lipids 28:475-477, 1993. PMID: 8316057
 
Rader DJ, Schaefer JR, Lohse P, Ikewaki K, Thomas F, Harris WS, Zech LA, Dujovne CA, and Brewer HB. Increased production of apolipoprotein A-I associated with elevated plasma levels of high-density lipoproteins, apolipoprotein A-I, and lipoprotein A-I in a patient with familial hyperalphalipoproteinemia. Metabolism 42:1429-1434, 1993. PMID: 8231838
 
Harris WS, Windsor SL, and Caspermeyer JJ. Modification of Lipid-related Atherosclerosis Risk Factors by w3 Fatty Acid Ethyl Esters in Hypertriglyceridemic Patients. J Nutr Biochem 4:706-712, 1993. Not available.
 
Dujovne CA, Eff J, Ferraro L, Goldstein RJ, Gotto AM, Hall WD, Harris WS, Held SJ, Herd A, Hunninghake DB, Johnson BF, and Sztern MI. Comparative effects of atenolol versus celiprolol on serum lipids and blood pressure in hyperlipidemic and hypertensive subjects. Am J Cardiol 72:1131-1136, 1993. PMID: 8237801
 
Dujovne CA, Harris WS, Gerrond LLC, Fan JY, Muzio F. Comparison of the effects of probucol versus vitamin E on ex vivo oxidation susceptibility of lipoproteins in hyperlipoproteinemia. Am J Cardiol 74:38-42, 1994. PMID: 8017303
 
Harris WS, Held SJ, Dujovne CA. Comparison of two scoring systems used to monitor diets in outpatient clinical trials. J Cardiovasc Risk 2:359-365, 1995. PMID: 8536155
 
O’Keefe JH Jr, Harris WS, Nelson J, Windsor SL. Effects of pravastatin with niacin or magnesium on lipid levels and postprandial lipemia. Am J Cardiol. 76: 480-484, 1995. PMID: 7653448
 
Kholodova YD, Harris WS. Identification and characteristic of LDL-subfractions in human plasma. Ukrainian J Biochem 67:67-72, 1995. PMID: 8867313
 
Rambjør GS, Wålen AI, Windsor SL, Harris WS. Eicosapentaenoic acid is primarily responsible for hypotriglyceridemic effect of fish oil in humans. Lipids 31:S45-S49, 1996. PMID: 8729093
 
Harris WS. n-3 fatty acids and lipoproteins: Comparison of results from human and animal studies. Lipids 31:243-252, 1996. PMID: 8900453
 
Harris WS, Rambjør GS, Windsor SL, Diederich D. n-3 fatty acids and urinary excretion of nitric oxide metabolites in humans. Am J Clin Nutr 65:459-64, 1997. PMID: 9022531
 
Harris WS, Hustvedt BE, Hagen B, Green MH, Drevon CA. Omega-3 fatty acids enhance chylomicron clearance in the rat. J Lipid Res 38:503-515, 1997. PMID: 9101431 
 
Harris WS, Windsor SL, Newton FA, Gelfand RA. Inhibition of Cholesterol Absorption with CP-148,623 lowers serum cholesterol in humans. Clin Pharmacol Ther 61:385-389, 1997. PMID: 9084463
 
Harris WS, Lu GP, Rambjør GS, Wålen AI, Ontko JA, Cheng Q, Windsor SL. Influence of w3 fatty acid supplementation on the endogenous activities of plasma lipases. Am J Clin Nutr 66:254-260, 1997. PMID: 9250102
 
Harris WS. n-3 Fatty acids and serum lipoproteins: animal studies. Am J Clin Nutr 65:1611S-1616S, 1997. PMID: 9129501
 
Harris WS. n-3 Fatty acids and serum lipoproteins: human studies. Am J Clin Nutr 65:1645S-1654S, 1997. PMID: 9129504
 
Ziogas G, Thomas TR, Harris WS. Exercise training, postprandial hypertriglyceridemia and LDL subfraction distribution. Med Sci Sports Exerc 29:986-991, 1997. PMID: 9268954
 
Thomas TR, Ziogas G, Harris WS. Influence of fitness status on VLDL subfractions and lipoprotein(a) in men and women. Metabolism 46:1178-1183, 1997. PMID: 9322803
 
Harris WS, Dujovne CA, Windsor SL, Gerrond LLC, Newton FA, Gelfand RA. Inhibiting cholesterol absorption with CP 88,818 (b-tigogenin cellobioside; tiqueside): Studies in normal and hyperlipidemic subjects. J Cardiovasc Pharmacol30:55-60, 1997. PMID: 9268221
 
Harris WS, Ginsberg H, Arunakul N, Shachter NS, Windsor SL, Adams M, Berglund L, Osmundsen K. Safety and efficacy of Omacor in severe hypertriglyceridemia. J Cardiovasc Risk 4:385-391, 1997.  PMID: 9865671
 
Lu GP, Windsor SL, Harris WS. Omega-3 fatty acids alter lipoprotein subfraction distributions and the in vitro conversion of very low density lipoproteins to low density lipoproteins. J Nutr Biochem, 10:151-158, 1999. PMID: 15539283
 
Harris WS, Gowda M, Kolb JW, Strychacz CP, Vacek JL, Jones PG, Forker A, O’Keefe JH, McCallister BM. A randomized, controlled trial of the effects of remote, intercessory prayer on outcomes in patients admitted to the coronary care unit. Arch Intern Med 159:2273-2278, 1999.  PMID: 10547166
 
Aleswad K, Pogson GW, Harris WS, Sherwani K, Bell HH. Effects of phenytoin, niacin, gemfibrozil and omega-3 fatty acids on high density lipoproteins in patients with hypoalphalipoproteinemia. Preventive Cardiol, 2:144-150, 1999. Not available.
 
Dujovne CA, Harris WS, Altman R, Overhiser RW, Black DM. Effect of Atorvastatin on Hemorheologic-Hemostatic Parameters and Serum Fibrinogen Levels in Hyperlipidemic Patients. Am J Cardiol 85:350-353, 2000. PMID: 11078305
 
Bybee KA, O’Keefe JH, Harris WS, Garg S, George SJ, Bateman TM. Lipid risk factor correlates of ischemic heart disease as diagnosed by myocardial perfusion scintigraphy. Prev Cardiol 3:154-159, 2000. PMID: 11834939
 
Park Y, Grellner WJ, Harris WS, and Miles JM: A new method for the study of chylomicron kinetics in vivo. Am J Physiol 279:E1258-63, 2000. PMID: 11093912
 
Park Y, Damron BD, Miles JM, and Harris WS. Measurement of human chylomicron triglyceride clearance with labeled commercial lipid emulsion. Lipids 36:115-120, 2001. PMID: 11269690
 
Miles JM, Park Y, Harris WS. Lipoprotein lipase and triglyceride-rich lipoprotein metabolism. Nutr Clin Pract 16:273-279, 2001. Not available.
 
Park Y, Schoene N, and Harris WS. Mean Platelet Volume as an Indicator of Platelet Activation: Methodological Issues. Platelets 13:301-306, 2002. PMID: 12189016
 
Yue P, Yuan B, Gerhard DS, Neuman RJ, Isley WL, Harris WS, Schonfeld G. Novel mutations of APOB cause apoB truncations undetectable in plasma and familial hypobetalipoproteinemia. Hum Mutat 20:110-6, 2002.  PMID: 12124991
 
Park Y, Harris WS. EPA, but not DHA, Decreases Mean Platelet Volume in Normal Subjects. Lipids 37:941-946, 2003. PMID: 11269690
 
Park Y, Harris WS. Omega-3 fatty acid supplementation accelerates chylomicron triglyceride clearance. J Lipid Res 44:455-463, 2003. PMID: 12562865
 
Miles JM, Woodridge D, Grellner JW, Windsor S, Isley WL, Klein S, Harris WS. Nocturnal and postprandial free fatty acid kinetics in normal and type 2 diabetic subjects. Diabetes 52:675-681, 2003.  PMID: 12606508
 
Park Y, Jones PG, Harris WS. Triacylglycerol-rich lipoprotein margination: A potential surrogate for whole body lipoprotein lipase activity and effects of EPA and DHA. Am J Clin Nutr 80:45-50, 2004. PMID: 15213026
 
Harris WS and von Schacky C. The Omega-3 Index: A New Risk Factor for Death from CHD? Preventive Medicine 39:212-220, 2004.  PMID: 15208005
 
Harris WS, Sands SA, Windsor SL, Ali HA, Stevens TL, Magalski A, Porter CB, Borkon AM. Omega-3 Fatty Acid Levels in Transplanted Human Hearts: Effect of Supplementation and Comparison with Erythrocytes. Circulation 110;1645-49, 2004. PMID: 15353491
 
O’Keefe JH, Jr., Captain BK, Jones PG, O’Keefe JH III, Harris WS. Atorvastatin Reduces Remnant Lipoproteins and Small Dense LDL Regardless of the Baseline Lipid Pattern. Preventive Cardiology 7:154-160, 2004. PMID: 15539961
 
 
Yue P, Isley WL, Harris WS, Rosipal S, Akin CD, Schonfeld G. Genetic variants of ApoE account for variability of plasma LDL and apoB levels in familial hypobetalipoproteinemia. Atherosclerosis 178:107-113, 2004. PMID: 15585207   
  
Sands SA, Reid KJ, Windsor SL, Harris WS. The impact of age, body mass index, and fish intake on the EPA and DHA content of human erythrocytes. Lipids 40:343-347, 2005. PMID: 16028715
 
Isley WL, Miles JM, Harris WS. The effect of high dose simvastatin on triglyceride rich lipoprotein metabolism in patients with type 2 diabetes mellitus. J Lipid Res 47:193-200, 2005. PMID: 16258165
 
Marso SP, Murphy JW, House JA, Safley DM, Harris WS. Metabolic syndrome-mediated inflammation following elective percutaneous coronary intervention. Diab Vasc Dis Res. 2:31-6, 2005. PMID: 16305070
 
O’Keefe JH, H Abuissa, A Sastre, DM Steinhaus, WS Harris. Effects of Omega-3 Fatty Acids on Resting Heart Rate, Heart Rate Recovery After Exercise, and Heart Rate Variability in Men With Healed Myocardial Infarctions and Depressed Ejection Fractions. Am J Cardiol 97:1127-1130, 2006. PMID: 16616012
 
Isley WL, Harris WS, Miles JM. The effect of high-dose simvastatin on free fatty acid metabolism in patients with type 2 diabetes mellitus. Metabolism 55:758-62, 2006. PMID: 16713435
 
Harris WS and Bulchandani D. Why do omega-3 fatty acids lower serum triglycerides? Curr Opin Lipidol 17:387-393, 2006. PMID: 16832161
 
Isley WL, Park Y, Harris WS. The Effect of High Dose Simvastatin on Platelet Size in Patients with Type 2 Diabetes Mellitus. Platelets. 17:292-295, 2006. PMID: 16928600
 
Harris WS, Assad B, Poston WC. Tissue n-6:n-3 fatty acid ratio and risk for cardiovascular disease. Am J Cardiology, 98:19i-26i, 2006. PMID: 16919513
 
Harris WS, Gonzales M, Laney N, Sastre A, Borkon AM. Effects of Omega-3 Fatty Acids on Heart Rate in Cardiac Transplant Recipients. Am J Cardiol 98:1393-1395, 2006. PMID: 17134636
 
Harris WS, Reid KJ, Sands SA, Spertus JA. Blood Omega-3 and Trans Fatty Acids in Middle-Aged Acute Coronary Syndrome Patients. Am J Cardiol 99:154-158, 2007. PMID: 17223410
 
Harris WS, DiRienzo MA, Sands SA, George C, Astwood JD, Jones PG, Eapen AK. Stearidonic Acid Supplementation Increases Red Blood Cell and Heart Omega 3 Index in Dogs. Lipids 42:325-333, 2007. PMID: 17406927
 
Harris WS, Poston WC, Haddock CK. Tissue n-3 and n-6 fatty acids and risk for coronary heart disease events. Atherosclerosis 193:1-10, 2007. PMID: 17507020
 
Isley WL, Miles JM, Harris WS. Pilot study of combined therapy with omega-3 fatty acids and niacin in atherogenic dyslipidemia. J Clin Lipidol 1:211-217, 2007. Not available.
 
Muzio F, Mondazzi L, Harris WS, Sommariva D, Branchi A. Effects of moderate variations in the macronutrient content of the diet on cardiovascular disease risk factors in obese patients with the metabolic syndrome. Am J Clin Nutr. 86:946-951, 2007. PMID: 17921369
 
Harris WS, Pottala JV, Sands SA, and Jones PG. Comparison of the effects of fish and fish oil capsules on the n-3 fatty acid content of blood cells and plasma phospholipids. Am J Clin Nutr 86 :1621-25, 2007. PMID: 18065578
 
Block RC, Harris WS, Reid KJ, Sands SA, Spertus JA. EPA and DHA in blood cell membranes from acute coronary syndrome patients and controls. Atherosclerosis. 197:821-828, 2008. PMID: 17875307
 
Cohen BE, Garg SK, Ali S, Harris WS, Whooley MA. Red blood cell EPA and DHA concentrations are positively associated with Socioeconomic status in patients with established coronary artery disease: Data from the Heart and Soul Study. J Nutrition 138 :1135-1140, 2008.  PMID: 18492846
 
Aarsetoey H, Pönitz V, Nilsen OB, Grundt H, Harris W, Nilsen DWT. Low levels of cellular omega-3 increases the risk of ventricular fibrillation during the acute ischaemic phase of a myocardial infarction. Resuscitation 78:258-264, 2008. PMID: 18556107
 
Block RC, Harris WS, Pottala JV. Determinants of blood cell omega-3 fatty acid content. The Open Biomarkers J 1:1-6, 2008.  PMID: 19953197
 
 
Larson MK, Ashmore JH, Harris KA, Vogelaar JL, Pottala JV, Sprehe M, Harris WS. Effects of Omega-3 Acid Ethyl Esters and Aspirin, Alone and in Combination, on Platelet Function in Healthy Subjects. J Thromb Haemost 2008;100:634-41. (Oct). PMID: 18841286
 
Harris WS, Lemke SL, Hansen SN, Goldstein DA, DiRienzo MA, Su H, Nemeth MA, Taylor ML, Ahmed G, George C. Stearidonic Acid-Enriched Soybean Oil Increased the Omega-3 Index, an Emerging Cardiovascular Risk Marker. Lipids 2008;43:805-811. (Sept) PMID: 18683001
 
Amin AA, Menon RA, Reid KJ, Harris WS, Spertus JA Acute Coronary Syndrome Patients With Depression Have Low Blood Cell Membrane Omega-3 Fatty Acid Levels. Psychosom Med. 2008;70:856-62. (Oct). PMID: 18842751
 
Farzaneh-Far R, et al. Inverse association of erythrocyte n-3 fatty acid levels with inflammatory biomarkers in stable coronary artery disease: The Heart and Soul Study. Atherosclerosis 2009; 205:538-43 (Aug). PMID: 19185299.
 
Duda MK, O'shea KM, Tintinu A, Xu W, Khairallah RJ, Barrows BR, Chess DJ, Azimzadeh AM, Harris WS, Sharov VG, Sabbah HN, Stanley WC. Fish Oil, But Not Flaxseed Oil, Decreases Inflammation and Prevents Pressure Overload-Induced Cardiac Dysfunction. Cardiovasc Res. 2008;81:310-327. ( Nov) PMID: 19015135
 
Clarke R, Shipley M, Armitage J, Collins R, Harris WS. Plasma phospholipid fatty acids and coronary heart disease in older men: Whitehall study of London Civil Servants. Brit J Nutr 2009 102:279-284. PMID: 19105853.
 
Block RC, Harris WS, Reid KJ, Spertus JA. Omega-6 and trans fatty acids in blood cell membranes: a risk factor for acute coronary syndromes? Am Heart J. 2008;156:1117-23. (Dec) NIHMS75965. PMCID:  PMC2596644.
 
Ali S, Garg SK, Cohen BE, Bhave P, Harris WS, Whooley MA. Association between omega-3 fatty acids and depressive symptoms among patients with established coronary artery disease: Data from the Heart and Soul Study. Psychother Psychosom. 2009;78:125-127 (Feb). PMID: 19223688
 
Maki KC, Lubin BC, Reeves MS, Dicklin MR, Harris WS. Prescription omega-3 acid ethyl esters and simvastatin 20 and 80 mg: effects in mixed dyslipidemia. J Clin Lipidol 2009;3:33-38 (Feb). (journal not indexed).
 
Shearer GC, Pottala JV, Spertus JA, Harris WS (2009) Red Blood Cell Fatty Acid Patterns and Acute Coronary Syndrome. PLoS ONE 4(5): e5444. doi:10.1371/journal.pone.0005444. PMID: 19185299
 
Shearer GC, Harris WS, Pedersen TL, Newman JW. Detection of omega-3 oxylipins in human plasma and response to treatment with omega-3 acid ethyl esters. J Lipid Res. 2009;51:1074-1081 PMID: 19671931.
 
Aarsetoey H, Volker P, Grundt H, Staines H, Harris WS, Nilsen DWT. (n-3) fatty acid content of red blood cells does not predict risk of future cardiovascular events following an acute coronary syndrome. J Nutr 2009;139:1–7. PMID: 19158216
 
Park Y, Harris WS. Dose-Dependent Effects of n-3 Polyunsaturated Fatty Acids on Platelet Activation in Mildly Hypertriglyceridemic Subjects. J Med Food. 2009,12:809-813. doi:10.1089/jmf.2008.1097. August. PMID: 19735181
 
Park Y, Harris WS. Dose-Response of n-3 Polyunsaturated Fatty Acids on Lipid Profile and Tolerability in Mildly Hypertriglyceridemic Subjects. J Med Food. 2009,12:803-808. doi:10.1089/jmf.2008.1250. August. PMID: 19735180
 
Harris WS, Thomas RM. Biological Variability of Blood Omega-3 Biomarkers. Clin Biochem 2010;43:338–340. PMID: 19733159
 
Carney RM, Freeland KE, Rubin EH, Rich MW, Steinmeyer BC, Harris WS. Omega-3 augmentation of sertraline in the treatment of depression in patients with coronary heart disease: a randomized controlled trial. JAMA 2009; 302:1651-1657 (October). PMID: 19843899
 
Shearer GS, Chen J, Chen Y, Harris WS. Myocardial infarction does not affect erythrocyte fatty acid profiles in rats. Prost Leuko Ess Fatty Acids 2009;81:411-416 (Sept).  PMID: 19775878
 
Farzaneh-Far R, Lin J, Epel ES, Harris WS, Blackburn EH, Whooley MA. Association of marine omega-3 fatty acid levels with telomeric aging in patients with coronary heart disease. JAMA 2010;303(3):250-257. PMID: 20085953
 
Billman GE, Nishijima Y, Belevych AE, Terentyev D, Xu1 Y, Haizlip1 KM, Monasky1 MM, Hiranandani1 N, Harris WS, Gyorke S, Carnes CA, Janssen PML. Effects of Dietary Omega-3 Fatty Acids on Ventricular Function in Dogs with Healed Myocardial Infarctions: In Vivo and In Vitro Studies. Am J Physiol Heart Circ Physiol. 2010;298(4):H1219-28. PMID: 20097770
 
Block RC, Duff R, Lawrence P, Kakinami L, Brenna JT, Shearer GC, Meednu N, Mousa S, Friedman A, Harris WS, Larson M, Georas S.The Effects of EPA, DHA, and Aspirin Ingestion on Plasma Lysophospholipids and Autotaxin. Prostagl Leukot Essent Fatty Acids. 2010;82:87-95. PMID: 20106646
 
Ebbesson SOE, Devereux RB, Cole S, Ebbesson LOE, Fabsitz RR, Haack K, Harris WS, Howard WH, Laston S, Lopez-Alvarenga JC, MacCluer JW, Okin PM, Tejero E, Voruganti VS, Wenger CR, Howard BV, Comuzzie AG. Heart Rate is Associated with Red Blood Cell Fatty Acid Concentration: the GOCADAN Study. Am Heart J, 2010;159:1020-1025. PMID: 20569715
 
Pottala JV, Garg S, Cohen BE, Whooley MA, Harris WS. Blood EPA and DHA Independently Predict All-Cause Mortality in Patients with Stable Coronary Heart Disease. The Heart and Soul Study. Circ:Qual Outcomes 2010;3 406-412. PMID: 20551373
 
Carney RM, Freedland KE, Stein PK, Steinmeyer BC, Harris WS, Rubin EH, Krone RJ, Rich MW. The Effect of Omega-3 Fatty Acids on Heart Rate Variability in Depressed Patients With Coronary Heart Disease. Psychosomat Med 2010;72(8):748-54. PMID: 20716712
 
Ebbesson SO, Tejero ME, López-Alvarenga JC, Harris WS, Ebbesson LO, Devereux RB, MacCluer JW, Wenger C, Laston S, Fabsitz RR, Howard BV, Comuzzie AG. Individual saturated fatty acids are associated with different components of insulin resistance and glucose metabolism: the GOCADAN study. Int J Circumpolar Health. 2010;69:344-51. PMID: 20719107.
 
Lemke SL, Vicini JL, Su H, Goldstein DA, Nemeth MA, Krul ES, Harris WS. Dietary intake of stearidonic acid enriched soybean oil increases the omega-3 index: randomized, double-blind clinical study of efficacy and safety. Am J Clin Nutr. 2010;92(4):766-75. PMID: 20739419.
 
Chen J, Shearer GS, Chen Q, Healy CL, Beyer AJ, Nareddy VB, Gerdes AM, Harris WS, O’Connell TD, Wang D. Omega-3 fatty acids prevent pressure overload-induced cardiac fibrosis through activation of cGMP/PKG signaling in cardiac fibroblasts. Circulation 2011;123:584-93. PMID: 21282499.
 
Yang R, Harris WS, Vernon K, Thomas AM, Qureshi N, Morrison DC, Van Way CW 3rd. Pre-feeding with omega-3 fatty acids suppresses inflammation following hemorrhagic shock. J Parenter Enteral Nutr. 2010;34:496-502. PMID: 20852177
 
Skulas-Ray AC, Kris-Etherton PM, Harris WS, Vanden Heuvel JP, Wagner PR, West SG. Dose response effects of omega-3 fatty acids on triglycerides, inflammation, and endothelial function in healthy people with moderate hypertriglyceridemia. Am J Clin Nutr. 2011;93:243-52. PMID:21159789.
 
Larson MK, Shearer GC, Ashmore JH, Anderson-Daniels JM, Graslie EL, Tholen JT, Vogelaar JL, Korth AJ, Nareddy V, Sprehe M, Harris WS. Omega-3 fatty acids modulate collagen signaling in human platelets. Prostaglandins Leukot Essent Fatty Acids. 2011;84:93-8. PMID: 21177087.
 
Hu S, Shearer GC, Steffes MW, Harris WS, Bostom AG. Once-daily extended-release niacin lowers serum phosphorus concentrations in patients with metabolic syndrome dyslipidemia. Am J Kidney Dis. 2011;57:181-2. PMID: 20888102.
 
Aarsetøy H, Aarsetøy R, Lindner T, Staines H, Harris WS, Nilsen DWT. Low Levels of the Omega-3 Index are Associated with Sudden Cardiac Arrest and Remain Stable in Survivors in the Subacute Phase. Lipids 2011;46:151-61. PMID:21234696
 
Moyers B, Farzaneh-Far R, Harris WS, Garg S, Na B, Whooley MA. Relation of Whole Blood n-3 Fatty Acid Levels to Exercise Parameters in Patients With Stable Coronary Artery Disease (from the Heart and Soul Study). Am J Cardiol. 2011;107:1149-54. PMID:21306696
 
Sala-Vila A, Harris WS, Cofán M, Pérez-Heras AM, Pintó X, Lamuela-Raventós RM, Covas M-I, Estruch R, Ros E. Determinants of the omega-3 index in a Mediterranean population at increased risk for coronary heart disease. Brit J Nutr 2011; 106:425-31. PMID:21450116.
 
 
Salisbury AC, Amin AP, Harris WS, Chan PS, Gosch KL, Rich MW, O'Keefe JH Jr, Spertus JA. Predictors of omega-3 index in patients with acute myocardial infarction. Mayo Clin Proc. 2011;86:626-32. PMID: 21719619
 
 
Salisbury AC, Harris WS, Amin AP, Reid KJ, O'Keefe Jr JH, Spertus JA. Relation Between Red Blood Cell Omega-3 Fatty Acid Index and Bleeding During Acute Myocardial Infarction. Am J Cardiol. 2012;109:13-18. PMID:21944672
 
Dewell A, Marvasti FF, Harris WS, Tsao PS, Gardner CD. Dose-Dependent Effects of Plant and Marine Omega-3 Fatty Acids on Inflammatory Markers in Insulin Resistant Adults. A Randomized Controlled Trial. J Nutrition 2011;141:2166-71.
 
Shearer GC, Savinova OV, Harris WS. Fish oil – How does it reduce triglyceride levels? Biochim Biophys Acta 2012;1821:843-851. PMID: 22041134
 
Hussey EK, Portelli S, Fossler MJ, Gao F, Harris WS, Blum RA, Lates CD, Gould E, Abu-Baker O, Johnson S, Reddy KK. Relative bioavailability of an emulsion formulation for omega-3-acid ethyl esters compared to the commercially available LOVAZA: A randomized, parallel group single-dose study followed by repeat dosing in healthy volunteers. Clin Pharm Drug Dev 2012;1:14-23. PMID:22279144
 
Krul ES, Lemke SL, Mukherjea R, Taylor ML, Goldstein DA, Su H, Liu P, Lawless A, Harris WS, Maki KC. Effects of Duration of Treatment and Dosage of Eicosapentaenoic Acid and Stearidonic Acid on Red Blood Cell Eicosapentaenoic Acid Content. Prostagl Leuko Essent FA 2012;86:51-59. PMID:22064208
 
Tan ZS, Harris WS, Beiser AS, Au R, Himali JJ, Debette S, Pikula A, DeCarli CS, Wolf PA, Vasan RS, Robins SJ, Seshardi S. Red Blood Cell Omega-3 Fatty Acid Levels and Markers of Accelerated Brain Aging. Neurology 2012;78:658-664. PMID:22371413
 
Block RC, Dier U, Calderonartero P, Shearer GC, Kakinami L, Larson MK, Harris WS, Georas S, Mousa SA. The Effects of EPA+DHA and Aspirin on Inflammatory Cytokines and Angiogenesis Factors. World J Cardiovasc Dis 2012;2:14-19.
 
Pottala JV, Talley JA, Churchill SW, Lynch DA, von Schacky C, Harris WS. Red blood cell fatty acids are associated with depression in a case-control study of adolescents. Prostaglandins Leukot Essent Fatty Acids. 2012;86:161-165. PMID: 22464051
 
Harris WS, Pottala JV, Vasan RS, Larson MG, Robins SJ. Changes in Erythrocyte Membrane Trans and Marine Fatty Acids between 1999 and 2006 in Older Americans. J Nutrition 2012;142(7):1297-303. PMID:22623386.
 
Voruganti VS, Higgins PB, Ebbesson SOE, Kennish J, Göring HHH, Haack K, Laston S, Drigalenko E, Wenger CR, Harris WS, Fabsitz RR, Devereux RB, MacCluer JW, Curran JE, Carless MA, Johnson MP, Moses EK, Blangero J, Umans JK, Howard BV, Cole SA, Comuzzie AG. Variants in CPT1A, FADS1, and FADS2 are associated with higher levels of estimated plasma and erythrocyte delta-5 desaturases in Alaskan Eskimos. Front Genet May 2012;3:86 (article no.). PMID:22701466
 
Harris WS, Pottala JV, Lacey SM, Vasan RS, Larson MG, Robins SJ. Clinical correlates and heritability of erythrocyte eicosapentaenoic and docosahexaenoic acid content in the Framingham Heart Study. Atherosclerosis 2012;225:425-31. PMID:22727409
 
Johnston DT, Deuster PA, Harris WS, MacRae H, Dretsch MN. Red blood cell omega-3 fatty acid levels and neurocognitive performance in deployed U.S. Servicemembers. Nutr Neurosci 2013;16:30-38. PMID:22748167
 
Pottala JV, Espeland MA, Polreis J, Robinson JG, Harris WS. Correcting the effects of -20°C storage and aliquot size on erythrocyte fatty acid content in the Women’s Health Initiative. Lipids 2012;47:835-46. PMID:22782370
 
Skulas-Ray AC, Kris-Etherton PM, Harris WS, West SG. Effects of marine-derived omega-3 fatty acids on systemic hemodynamics at rest and during stress: a dose response study. Ann Behav Med 2012;44:301-8. PMID:22865498
 
Shearer GC, Pottala JV, Hansen SN, Brandenburg V, Harris WS. Effects of prescription niacin and omega-3 fatty acids on lipids and vascular function in metabolic syndrome: a randomized controlled trial. J Lipid Res 2012;53:2429-35. PMID: 22892157
 
Harris WS, Pottala JV, Varvel SA, Borowski JJ, Ward JN, McConnell JP. Erythrocyte Omega-3 Fatty Acids Increase and Linoleic Acid Decreases with Age: Observations in 160,000 Patients. Prostaglandins Leukot Essent Fatty Acids. 2013;88(4):257-63. PMID:23375840.
 
Harris WS, Kennedy KF, O’Keefe JH, Spertus JA. Red blood cell fatty acid levels improve GRACE score prediction of 2-yr mortality in patients with myocardial infarction. Intl J Cardiology 2013;168:53-59. PMID: 23044429
 
Metkus TS, Timpone J, Leaf D, Goetz M, Harris WS, Brown T. The Effect of Omega-3-acid Ethyl Esters on Lipids, Systemic Inflammation, and Bone Turnover in HIV-infected patients with Hypertriglyceridemia: A Randomized, Placebo-Controlled Trial. HIV Med 2013;14:530-9. PJMID: 23683266
 
Grenon SM, Conte MS, Nosova E, Alley H, Chong K, Yen P, Harris WS, Vittinghoff E, Owens CD. Association between n-3 polyunsaturated fatty acid content of red blood cells and inflammatory biomarkers and vascular function in patients with peripheral artery disease. J Vasc Surg, 2013;58:1283-90. PMID: 23830313
 
Harris WS, Varvel SA, Pottala JV, Warnick GR, McConnell JP. The Comparative Effects Of An Acute Dose Of Fish Oil On Omega-3 Fatty Acid Levels in Red Blood Cells Versus Plasma: Implications for Clinical Utility. J Clin Lipidol 2013;7:433-440. PMID: 24079284.
 
Shah RV, Abbasi SA, Neilan TG, Hulten E, Coelho-Filho O, Hoppin A, Levitsky L, de Ferranti S, Rhodes ET, Traum A, Goodman E, Feng H, Heydari B, Harris WS, Hoefner DM, McConnell JP, Seethamraju R, Rickers C, Kwong RY, Jerosch-Herold M. Myocardial tissue remodeling in adolescent obesity. J Am Heart Assoc. 2013;2(4):e000279. PMID:23963758
 
Ammann EM, Pottala JV, Harris WS, Espeland MA, Wallace R, Denburg NL, Carnahan RM, Robinson JG. Omega-3 fatty acids and domain-specific cognitive aging: Secondary analyses of data from WHISCA. Neurology. 2013 Oct 22;81(17):1484-91 PMID:24068783
 
Wu JH, Marchioli R, Silletta MG, Macchia A, Song X, Siscovick DS, Harris WS, Masson S, Latini R, Albert C, Brown NJ, Lamarra M, Favaloro RR, Mozaffarian D. Plasma phospholipid omega-3 fatty acids and incidence of postoperative atrial fibrillation in the OPERA trial. J Am Heart Assoc. 2013;2:e000397. PMID: 24145742
 
Persons JE, Robinson, JG, Ammann EM, Coryell WH, Espeland MA, Harris WS, Manson JE, Fiedorowicz JG. Omega-3 Fatty Acid Biomarkers and Subsequent Depressive Symptoms. Intl J Geriatric Psychiatry 2013 (in press).
 
Grenon SM, Owens CD, Alley H, Chong K, Yen PK, Harris W, Hughes-Fulford M, Conte MS. n-3 Polyunsaturated fatty acids supplementation in peripheral artery disease: the OMEGA-PAD trial. Vasc Med. 2013;18:263-74. PMID:24052491
 
Flock MR, Skulas-Ray AC, Harris WS, Etherton TD, Fleming JA, Kris-Etherton PM. Determinants of Erythrocyte Omega-3 Fatty Acid Content in Response to Fish Oil Supplementation: A Dose-Response Randomized Controlled Trial. J Am Heart Assoc. 2013;2:e000513.
 
Augustine AH, Lowenstein LM, Harris WS, Shearer GC, Block RC. Treatment with omega-3 fatty acid ethyl-ester alters fatty acid composition of lipoproteins in overweight or obese adults with insulin resistance. Prostagland Leukotr Ess Fatty Acids 2013 (in press).
 
Harris WS, Schmitt TL. Unexpected Similarity in Red Blood Cell Docosahexaenoic Acid and Arachidonic Acid Levels Between Bottlenose Dolphins and Humans. PLEFA 2013 (in press).

Pottala JV, Yaffe K, Robinson JG, Espeland MA, Wallace RB, Harris WS. Higher RBC EPA+DHA corresponds with larger total brain and hippocampal volumes: WHIMS-MRI study. Neurology 2014 (in press).

Reviews, Commentaries, Letters and Book Chapters

Harris, WS. Health Effects of Omega-3 Fatty Acids. Contemp Nutr 10:No 8, 1985.

Dujovne CA, Harris WS. Approach to diagnosis and treatment of subjects at risk for dyslipidemia-induced atherosclerotic cardiovascular disease. Pract Cardiol (special issue) May, 1988, pp. 24-30.

Harris, WS. N-3 fatty acids and LDL cholesterol or looking beyond the risk factors. N-3 News 3:1-3, Dec., 1988.

Harris WS, Dujovne CA. Management of hypercholesterolemia. Curr Opin Cardiol 4:705-710, 1989.

Harris WS. Can fish oil retard atherosclerosis? Pract Cardiol 15:25-32, 1989.

Dujovne CA, Harris WS. The Pharmacological Treatment of Dyslipidemia. Ann Rev Pharmacol Toxicol 29:265-288, 1989. PMID: 2658772

Dujovne CA, Harris WS. The role of fish oils in the treatment of hyperlipidemia. Mod Med 57:69-79, 1989.

Harris WS. Omega-3 fatty acids: effects on lipid metabolism. Curr Opin Lipidol 1:5-11, 1990.

Dujovne CA, Harris WS. Variables in Serum Lipid Measurements. Do they impede proper diagnosis and treatment of dyslipidemia? Arch Intern Med 150:1583-1585, 1990.

Harris, WS. Whither N-3 Fatty Acids? J Appl Nutr 44:45-46, 1992.

Harris WS. Effects of n-3 Fatty Acids on Human Lipoprotein Metabolism. In: Clinical Pharmacology, vol. 5. “Fish, Fish Oil, and Human Health.” Ed. JC Frolich, C von Schacky, 1992, pp. 88-97.

Harris WS. The Absorption of n-3 Fatty Acids in Different Chemical Forms. In: Clinical Pharmacology, vol. 5. “Fish, Fish Oil, and Human Health.” Ed. JC Frolich, C von Schacky, 1992, pp. 40-45.

Harris WS. The benefits and pathologies from excesses and deficiencies of dietary fatty acids. Curr Opin Endocrin Diab 1:260-266, 1994.

O’Keefe JH, Nelson J, Harris WS. Lifestyle change for coronary artery disease. Postgrad Med 99:89-106, 1996. PMID: 8632976

Harris WS. Dietary fish oil and blood lipids. Curr Opin Lipidol 7:3-7, 1996. PMID: 8925185

Harris WS. Control of dyslipidemia with truly practical doses of omega-3 fatty acids. CVD/Lipids Dialog. Issue 7, March 1998.

O'Keefe JH Jr, Miles JM, Harris WS, Moe RM, McCallister BD. Improving the adverse cardiovascular prognosis of type 2 diabetes. Mayo Clinic Proceedings. 74:171-80, 1999.

Harris WS. Non-pharmacologic treatment of hypertriglyceridemia: focus on fish oils. Clin Cardiol 22:II-40-43, 1999. PMID: 10376196

Harris WS. n-3 fatty acids and human lipoprotein metabolism: An update. Lipids 34:S257-258, 1999. PMID: 10419172

O’Keefe JH, Harris WS. From Inuit to Implementation: Omega-3 fatty acids come of age. Mayo Clin Proc 75:607-614, 2000. PMID: 10852422

O’Keefe JH, Harris WS. Omega-3 fatty acids: Time for clinical implementation? Am J Cardiol 85:1239-1241, 2000. PMID: 10802008

Harris WS. w3 fatty acids and human chylomicron metabolism. World Rev Nutr Diet 88:163-176, 2001. PMID: 11935949

Harris WS, O’Keefe JH. Cardioprotective Effects of Omega-3 Fatty Acids. Nutr Clin Pract, 16:6-12, 2001.

Harris WS, Isley WL. Clinical Trial Evidence for the Cardioprotective Effects of Omega-3 Fatty Acids. Curr Athero Rep 3:174-9, 2001. PMID: 11177663

Harris WS. International Workshop on Omega-3 Fatty Acids, Diabetes and Cardiovascular Risk - Executive Summary. Eur. J. Lipid Sci. Technol.103:187, 2001.

Harris WS. Omega-3 long-chain PUFA and triglyceride lowering: minimum effective intakes. Europ Heart J 3:D59-D61, 2001. 

Kris-Etherton PM, Harris WS, Appel LJ. Fish Consumption, Fish Oil, Omega-3 Fatty Acids and Cardiovascular Disease. A Scientific Statement from the American Heart Association. Circulation 106:2747-57, 2002.

Harris WS, Park YS, Isley WL. Cardiovascular Disease and Long-Chain Omega-3 Fatty Acids. Curr Opin Lipidol 14:9-14, 2003. PMID: 12544655

Harris WS. N-3 long chain polyunsaturated fatty acids reduce risk of coronary heart disease death: extending the evidence to the elderly. Am J Clin Nutr 77:279-280, 2003. PMID: 12540382

Isley WL, Harris WS. Fish Oils. Not Just for Eskimos Anymore. Practical Diabetology September 2003; 42-46.

O’Keefe JH, Cordain L, Harris WS, Moe RM, Vogel R. Optimal LDL is to 50 to 70: Lower is Better and Physiologically Normal. J Am Coll Cardiol 44:2142-46, 2004.

Harris WS. Fish oil supplementation: Evidence for health benefits. Cleve Clin J Med 71:208-221, 2004. PMID: 15055244

Harris WS, O’Keefe JH. Fish oil supplementation for cardioprotection: How much is enough? How much is safe? Consultant 45:620-624, 2005.

Harris WS. Alpha-linolenic acid: A Gift from the Land? Circulation 111:2872-74, 2005. PMID: 15939831

Harris WS. The Omega-3 Index: A Novel Predictor of Risk for Cardiac Mortality. Nutrition and the M.D., vol. 31, Sept 2005.

Harris WS. Extending the Cardiovascular Benefits of Omega-3 Fatty Acids. Curr Athero Reports 2005; 7:375-380. PMID: 16105481

Gebauer SK, Psota TL, Harris WS, Kris-Etherton PM. N-3 fatty acid dietary recommendations and food sources to achieve essentiality and cardiovascular benefits. Am J Clin Nutr 2006; 83(suppl): 1526S-1535S. PMID: 16841863

Sacks FM, Lichtenstein A, Van Horn L, Harris WS, Kris-Etherton PM, Winston M for the American Heart Association Nutrition Committee. Soy Protein, Isoflavones, and Cardiovascular Health: An American Heart Association Science Advisory for Professionals. Circulation 113:1034-1044, 2006.

Wang C, Harris WS, Chung M, Lichtenstein AH, Balk EM, Kupelnick B, Jordan HS, Lau J. n-3 Fatty Acids from Fish or Fish Oil Supplements, but not Alpha-Linolenic Acid, Benefit Cardiovascular Disease Outcomes in Primary and Secondary Prevention Studies: A Systematic Review. Am J Clin Nutr 84:5-17, 2006. PMID: 16825676

Scandale S, Lee DT and Harris WS. Omega-3 fatty acids; Fish oil use in primary care practice. Family Pract Recertif. 28:20-22,25-28,31, 2006

Harris WS. The omega-6/omega-3 ratio and cardiovascular disease risk: uses and abuses. Curr Atheroscler Rep. 8:453-459, 2006. PMID: 17045070

Lichtenstein AH, Appel LJ, Brands, M, Carnethon M, Daniels S, Franch HA, Franklin B, Kris-Etherton P, Harris WS, Howard B, Karanja N, Lefevre M, Rudel L, Sacks F, Van Horn L, Winston M, and Wylie-Rosett J. Diet and lifestyle recommendations revision 2006: a scientific statement from the American Heart Association Nutrition Committee. Circulation. 2006 Jul 4;114:82-96. PMID: 16785338

Bersot T, Haffner S, Harris WS, Kellick KA, Morris. Hypertriglyceridemia: management of atherogenic dyslipidemia. J Fam Pract. 55:S1-8, 2006. PMID: 16822443

Harris WS. Omega-3 Fatty Acids and Bleeding: Cause for Concern? Am J Cardiol 2007;99[suppl]:44C-46C. PMID: 17368278

von Schacky C and Harris WS. Cardiovascular benefits of omega-3 fatty acids. Cardiovasc Res 73:310-315, 2007. PMID: 16979604

Harris WS. Omega-3 Fatty Acids and Cardiovascular Disease: A Case for Omega-3 Index as a New Risk Factor. Pharma Res 55:217-273, 2007.

Lucas M, Harris WS. Risks and benefits of fish intake (letter). JAMA 297:585, 2007.

Harris WS. N-3 fatty acid fortification: opportunities and obstacles. Brit J Nutr 97:593-595, 2007.

Harris WS. Does treatment with eicosapentaenoic acid prevent major coronary events in patients with hypercholesterolemia? Nat Clin Pract Cardiovasc Med. October 2007;4:532-3. PMID: 17700546

Von Schacky C, Harris WS. Cardiovascular risk and the omega-3 index. J Cardiovasc Med 8:S46-S49, 2007. PMID: 17876200

Harris WS. International recommendations for consumption of long-chain omega-3 fatty acids. J Cardiovasc Med 8:S50-S52, 2007. PMID: 17876201

Stanley JC, Elsom RL, Calder PC, Griffin BA, Harris WS, Jebb SA, Lovegrove JA, Moore CS, Riemersma RA, Sanders TA. UK Food Standards Agency Workshop Report: the effects of the dietary n-6:n-3 fatty acid ratio on cardiovascular health. Br J Nutr. 2007;98:1305-10.

Hansen SN and Harris WS. New Evidence for the Cardiovascular Benefits of Long Chain Omega-3 Fatty Acids. Curr Athero Rpts 2007;9:434-440.

Lee JH, O’Keefe JH, Lavie CJ, Marchioli R, and Harris WS. Omega-3 Fatty Acids for Cardio-protection. Mayo Clinic Proc 2008;83:324-332.

Harris WS, Tighe AP, Miller M, Davidson M, Schaefer EJ. Omega-3 Fatty Acids and Coronary Heart Disease Risk: Clinical and Mechanistic Perspectives. Atherosclerosis 2008 ;197:12-24. PMID: 18160071

Harris WS, Von Schacky C. Omega-3 fatty acids, acute coronary syndromes and sudden cardiac death. Curr Cardiovasc Risk Rpt 2008;2:161-166.

Harris WS. Cardiovascular Risk and Alpha-Linolenic Acid: Can Costa Rica Clarify? (editorial) Circulation 2008;118:323-324.

Harris WS. The omega-3 index as a risk factor for coronary heart disease. Am J Clin Nutr 2008;87(suppl):1997S-2002S.

Deckelbaum RJ, Leaf A, Mozaffarian D, Jacobsen TA, Harris WS, and Akabas SR. Conclusions and recommendations of the symposium, “Beyond Cholesterol: Prevention and Treatment of Coronary Heart Disease with N-3 Fatty Acids.” Am J Clin Nutr 2008;87(suppl):2010S-2012S.

Harris WS. You Are What You Eat Applies to Fish, Too. (editorial). J Am Diet Assoc 2008;108:1131-1133.

Harris WS. Omega-3 Fatty Acids: The “Japanese” Factor? J Am Coll Cardiol 2008;52:425-427.

Harris WS. N-3 Fatty Acids and Health: DaVinci’s Code. Am J Clin Nutr 2008;88:595-596.

Harris WS. Linoleic acid and coronary heart disease. Prostaglandins Leukot Essent Fatty Acids. 2008 Sep-Nov;79(3-5):169-71.

Harris WS, Jacobson TA. Omega-3 Fatty Acids. In: Clinical Lipidology: A Companion to Braunwald’s Heart Disease. Ed. CM Ballantyne. Saunders Elsevier, Philadelphia; 2009; pp.326-338.

Harris WS, Mozaffarian D, Rimm E, Kris-Etherton PM, Rudel LL, Appel LJ, Engler MM, Engler MB, Sacks F. Omega-6 Fatty Acids and Risk for Cardiovascular Disease. A Science Advisory from the American Heart Association Nutrition Committee. Circulation 2009;119:902-907. PMID: 19171857

Harris WS, Mozaffarian D, Lefevre M, Toner CD, Colombo J, Cunnane SC, Holden JM, Klurfeld DM, Morris MC, Whelan J. Towards Establishing Dietary Reference Intakes for Eicosapentaenoic and Docosahexaenoic Acids. J Nutrition 2009;139:804S-819S. PMID: 19244379

Brownawell AM, Harris WS, Hibbeln JR, Klurfeld DM, Newton I, Yates A. Assessing the environment for regulatory change for EPA and DHA nutrition labeling. Nutr Rev 2009;67:391-397. PMID: 19566599

Mulligan ML, Harris WS. Should pregnant women eat fish? J Reprod Med. 2009 May;54(5):263-6. PMID: 19517688

Harris WS. The Omega-3 Index: From biomarker to risk marker to risk factor. Curr Athero Rept 2009;11:411-417. Nov; PMID: 19852881

Harris WS. Substudies from JELIS. Curr Athero Rept 2009;11:399-400. Nov PMID: 19852879

Lee JH, O'Keefe JH, Lavie CJ, Harris WS. Omega-3 fatty acids: cardiovascular benefits, sources and sustainability. Nat Rev Cardiol. 2009 Oct 27. PMID: 19859067.

Kris-Etherton PM, Fleming J, Harris WS. The debate about n-6 polyunsaturated fatty acid recommendations for cardiovascular health. J Am Diet Assn 2010;10:201-204. doi: 10.1016/j.jada.2009.12.006. PMID: 20102846

Harris WS. Omega-3 and Omega-6 Fatty Acids: Partners in Prevention. Curr Opin Clin Nutr Metabol Care. 2010;13:125-129. (March) PMID: 20145438

Harris W. Omega-3 and atrial fibrillation (letter to editor). Thorac Cardiov Surg 2010;58:60.

Robinson JG, Ijioma N, Harris W. Omega-3 fatty acids and cognitive function in women. Women’s Health (Lond Engl). 2010 Jan;6(1):119-34. PMID: 20088735.

Harris WS. Blood omega-3 levels predict the rate of cellular aging. Lipid Spin (NLA publication) Spring, 2010.

Harris WS. Marine Omega-3 Fatty Acids and Plaque Stabilization. Curr Atheroscler Rep (2010) 12:357–358. PMID: 20697847.

Harris WS. The Omega-3 Index: Clinical Utility for Therapeutic Intervention. Curr Cardiol Rep. 2010 (Sept). 12:503–508. PubMed PMID: 20809235.

Harris WS, Klurfeld DM. Twentieth-century trends in essential fatty acid intakes and the predicted omega-3 index: evidence versus estimates. Am J Clin Nutr. 2011;93:907-908. PMID: 21430117

Brown WV, Bays H, Harris W, Miller M. Using omega-3 fatty acids in the practice of clinical lipidology. J Clin Lipidol. 2011;5:424-33.

Harris WS, Brouwer IA, Mozaffarian D. n-6 Fatty acids and risk for CHD: consider all the evidence. Brit J Nutr 2011;106:951-2; author reply 953-7.PMID: 21679479

Harris WS. Stearidonic Acid-Enhanced Soybean Oil: A Plant-Based Source of (n-3) Fatty Acids for Foods. J Nutr 2012;142:600S-604S

Harris WS. Stearidonic Acid as a ‘Pro-Eicosapentaenoic Acid’. Curr Opin Lipidol 2012, 23:30–34. PMID: 22186661

Deckelbaum RJ, Calder PC, Harris WS, Akoh CC, Maki KC, Whelan J, Banz WJ, Kennedy E. Conclusions and Recommendations from the Symposium, Heart Healthy Omega-3s for Food: Stearidonic Acid (SDA) as a Sustainable Choice. J Nutr. 2012;142:S641-S643.

Gillies PJ, Harris WS, Kris-Etherton PM. Omega-3 fatty acids in food and pharma: the enabling role of biotechnology. Curr Atheroscler Rep. 2011 Dec;13(6):467-73.

Harris WS. Omega-3 fatty acids: Are they still cardioprotective? Curr Opin Clin Nutr Metab Care, 2013 Mar;16(2):141-9. doi: 10.1097/MCO.0b013e32835bf380. PMID:23196817

Harris WS, von Schacky C, Park Y. Standardizing Methods for Assessing Omega-3 Fatty Acid Biostatus. In: The Omega-3 Fatty Acid Deficiency Syndrome. Editor: RK McNamara. Nova Science Publishers, Inc., pp. 385-398, 2013.

Barringer TA, Harris WS. Omega-3 Fatty Acid Deficiency and Cardiovascular Disease. In: The Omega-3 Fatty Acid Deficiency Syndrome. Editor: RK McNamara. Nova Science Publishers, Inc., pp. 213-232, 2013.

Harris WS, De Caterina R, Malik PE. DHA ethyl esters not effective? (Letter). Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):E2259. doi: 10.1073/pnas.1305038110. PMID: 23671065

Harris WS. Assessing Fatty Acid Biostatus: Red Blood Cells or Plasma? Lipid Technol 2013;25:179-181.

Flock MR, Harris WS, Kris-Etherton PM. Long-chain omega-3 fatty acids: time to establish a dietary reference intake. Nutr Rev. 2013;71:692-707. PMID:24117792

Harris WS. Achieving optimal n-3 fatty acid status - the vegetarian’s challenge…. or not? Am J Clin Nutr 2013 (in press).

Harris WS, Dayspring TD, Moran TJ. Omega-3 fatty acids and Cardiovascular Disease: New Developments and Applications. Postgrad Med 2013;125:100-113.

Harris WS and Davidson MD. Omega-3 Fatty Acids and Risk for Prostate Cancer: Unwarranted extrapolations. J Natl Cancer Inst (letter to the editor). In press 2013

Block RC, Harris WS, Reid KJ, Sands SA, Spertus JA. EPA and DHA in blood cell membranes from acute coronary syndrome patients and controls. Atherosclerosis. 197:821-828, 2008. PMID: 17875307 

Cohen BE, Garg SK, Ali S, Harris WS, Whooley MA. Red blood cell EPA and DHA concentrations are positively associated with Socioeconomic status in patients with established coronary artery disease: Data from the Heart and Soul Study. J Nutrition 138 :1135-1140, 2008.  PMID: 18492846
 
Aarsetoey H, Pönitz V, Nilsen OB, Grundt H, Harris W, Nilsen DWT. Low levels of cellular omega-3 increases the risk of ventricular fibrillation during the acute ischaemic phase of a myocardial infarction. Resuscitation 78:258-264, 2008. PMID: 18556107
 
Block RC, Harris WS, Pottala JV. Determinants of blood cell omega-3 fatty acid content. The Open Biomarkers J 1:1-6, 2008.  PMID: 19953197
 
Harris WS, Kris-Etherton PM, Harris KA. Intake of Long-Chain Omega-3 Fatty Acids Associated with Reduced Risk for Death from Coronary Heart Disease in Healthy Adults. Curr Athero Reports 10:503-9, 2008. (Oct) PMID: 18937898
 
Larson MK, Ashmore JH, Harris KA, Vogelaar JL, Pottala JV, Sprehe M, Harris WS. Effects of Omega-3 Acid Ethyl Esters and Aspirin, Alone and in Combination, on Platelet Function in Healthy Subjects. J Thromb Haemost 2008;100:634-41. (Oct). PMID: 18841286
 
Harris WS, Lemke SL, Hansen SN, Goldstein DA, DiRienzo MA, Su H, Nemeth MA, Taylor ML, Ahmed G, George C. Stearidonic Acid-Enriched Soybean Oil Increased the Omega-3 Index, an Emerging Cardiovascular Risk Marker. Lipids 2008;43:805-811. (Sept) PMID: 18683001
 
Amin AA, Menon RA, Reid KJ, Harris WS, Spertus JA Acute Coronary Syndrome Patients With Depression Have Low Blood Cell Membrane Omega-3 Fatty Acid Levels. Psychosom Med. 2008;70:856-62. (Oct). PMID: 18842751
 
Farzaneh-Far R, et al. Inverse association of erythrocyte n-3 fatty acid levels with inflammatory biomarkers in stable coronary artery disease: The Heart and Soul Study. Atherosclerosis 2009; 205:538-43 (Aug). PMID: 19185299.
 
Duda MK, O'shea KM, Tintinu A, Xu W, Khairallah RJ, Barrows BR, Chess DJ, Azimzadeh AM, Harris WS, Sharov VG, Sabbah HN, Stanley WC. Fish Oil, But Not Flaxseed Oil, Decreases Inflammation and Prevents Pressure Overload-Induced Cardiac Dysfunction. Cardiovasc Res. 2008;81:310-327. ( Nov) PMID: 19015135
 
Clarke R, Shipley M, Armitage J, Collins R, Harris WS. Plasma phospholipid fatty acids and coronary heart disease in older men: Whitehall study of London Civil Servants. Brit J Nutr 2009 102:279-284. PMID: 19105853.
 
Block RC, Harris WS, Reid KJ, Spertus JA. Omega-6 and trans fatty acids in blood cell membranes: a risk factor for acute coronary syndromes? Am Heart J. 2008;156:1117-23. (Dec) NIHMS75965. PMCID:  PMC2596644.
 
Lee JH, O’Keefe JH, Lavie CJ, Marchioli R, and Harris WS. Omega-3 Fatty Acids for Cardio-protection. Mayo Clinic Proc 2008;83:324-332.
 
Harris WS, Tighe AP, Miller M, Davidson M, Schaefer EJ. Omega-3 Fatty Acids and Coronary Heart Disease Risk: Clinical and Mechanistic Perspectives. Atherosclerosis 2008 ;197:12-24. PMID: 18160071
 
Harris WS, Von Schacky C. Omega-3 fatty acids, acute coronary syndromes and sudden cardiac death. Curr Cardiovasc Risk Rpt 2008;2:161-166..
 
Harris WS. The omega-3 index as a risk factor for coronary heart disease. Am J Clin Nutr 2008;87(suppl):1997S-2002S.
 
Ali S, Garg SK, Cohen BE, Bhave P, Harris WS, Whooley MA. Association between omega-3 fatty acids and depressive symptoms among patients with established coronary artery disease: Data from the Heart and Soul Study. Psychother Psychosom. 2009;78:125-127 (Feb). PMID: 19223688
 
Maki KC, Lubin BC, Reeves MS, Dicklin MR, Harris WS. Prescription omega-3 acid ethyl esters and simvastatin 20 and 80 mg: effects in mixed dyslipidemia. J Clin Lipidol 2009;3:33-38 (Feb). 
 
Harris WS, Jacobson TA. Omega-3 Fatty Acids. In: Clinical Lipidology: A Companion to Braunwald’s Heart Disease. Ed. CM Ballantyne. Saunders Elsevier, Philadelphia; 2009; pp.326-338.
 
Harris WS, Mozaffarian D, Rimm E, Kris-Etherton PM, Rudel LL, Appel LJ, Engler MM, Engler MB, Sacks F. Omega-6 Fatty Acids and Risk for Cardiovascular Disease. A Science Advisory from the American Heart Association Nutrition Committee. Circulation 2009;119:902-907. PMID: 19171857
 
Harris WS, Mozaffarian D, Lefevre M, Toner CD, Colombo J, Cunnane SC, Holden JM, Klurfeld DM, Morris MC, Whelan J. Towards Establishing Dietary Reference Intakes for Eicosapentaenoic and Docosahexaenoic Acids. J Nutrition 2009;139:804S-819S. PMID: 19244379
 
Brownawell AM, Harris WS, Hibbeln JR, Klurfeld DM, Newton I, Yates A. Assessing the environment for regulatory change for EPA and DHA nutrition labeling. Nutr Rev 2009;67:391-397. PMID: 19566599
 
Harris WS. The Omega-3 Index: From biomarker to risk marker to risk factor. Curr Athero Rept 2009;11:411-417. Nov; PMID: 19852881
 
Lee JH, O'Keefe JH, Lavie CJ, Harris WS. Omega-3 fatty acids: cardiovascular benefits, sources and sustainability. Nat Rev Cardiol. 2009 Oct 27. PMID: 19859067.
 
Kris-Etherton PM, Fleming J, Harris WS. The debate about n-6 polyunsaturated fatty acid recommendations for cardiovascular health. J Am Diet Assn 2010;10:201-204. doi: 10.1016/j.jada.2009.12.006. PMID: 20102846
 
Shearer GC, Pottala JV, Spertus JA, Harris WS (2009) Red Blood Cell Fatty Acid Patterns and Acute Coronary Syndrome. PLoS ONE 4(5): e5444. doi:10.1371/journal.pone.0005444.  PMID: 19185299
 
Shearer GC, Harris WS, Pedersen TL, Newman JW. Detection of omega-3 oxylipins in human plasma and response to treatment with omega-3 acid ethyl esters. J Lipid Res. 2009;51:1074-1081 PMID: 19671931.
 
Aarsetoey H, Volker P, Grundt H, Staines H, Harris WS, Nilsen DWT. (n-3) fatty acid content of red blood cells does not predict risk of future cardiovascular events following an acute coronary syndrome. J Nutr 2009;139:1–7. PMID: 19158216
 
Park Y, Harris WS. Dose-Dependent Effects of n-3 Polyunsaturated Fatty Acids on Platelet Activation in Mildly Hypertriglyceridemic Subjects. J Med Food. 2009,12:809-813. doi:10.1089/jmf.2008.1097. August. PMID: 19735181
 
Park Y, Harris WS. Dose-Response of n-3 Polyunsaturated Fatty Acids on Lipid Profile and Tolerability in Mildly Hypertriglyceridemic Subjects. J Med Food. 2009,12:803-808. doi:10.1089/jmf.2008.1250. August. PMID: 19735180
 
Harris WS, Thomas RM. Biological Variability of Blood Omega-3 Biomarkers. Clin Biochem 2010;43:338–340.  PMID: 19733159
 
Carney RM, Freeland KE, Rubin EH, Rich MW, Steinmeyer BC, Harris WS. Omega-3 augmentation of sertraline in the treatment of depression in patients with coronary heart disease: a randomized controlled trial. JAMA 2009; 302:1651-1657 (October). PMID: 19843899
 
Shearer GS, Chen J, Chen Y, Harris WS. Myocardial infarction does not affect erythrocyte fatty acid profiles in rats. Prost Leuko Ess Fatty Acids 2009;81:411-416 (Sept).  PMID: 19775878
 
Farzaneh-Far R, Lin J, Epel ES, Harris WS, Blackburn EH, Whooley MA. Association of marine omega-3 fatty acid levels with telomeric aging in patients with coronary heart disease. JAMA 2010;303(3):250-257. PMID: 20085953
 
Billman GE, Nishijima Y, Belevych AE, Terentyev D, Xu1 Y, Haizlip1 KM, Monasky1 MM, Hiranandani1 N, Harris WS, Gyorke S, Carnes CA, Janssen PML. Effects of Dietary Omega-3 Fatty Acids on Ventricular Function in Dogs with Healed Myocardial Infarctions: In Vivo and In Vitro Studies. Am J Physiol Heart Circ Physiol. Jan 22 2010 PMID: 20097770
 
Block RC, Duff R, Lawrence P, Kakinami L, Brenna JT, Shearer GC, Meednu N, Mousa S, Friedman A, Harris WS, Larson M, Georas S.The Effects of EPA, DHA, and Aspirin Ingestion on Plasma Lysophospholipids and Autotaxin. Prostagl Leukot Essent Fatty Acids. 2010 Jan 25. [Epub ahead of print] PMID: 20106646
 
Harris WS. Omega-3 and Omega-6 Fatty Acids: Partners in Prevention. Curr Opin Clin Nutr Metabol Care. 2010;13:125-129. (March) PMID: 20145438
 
Robinson JG, Ijioma N, Harris W. Omega-3 fatty acids and cognitive function in women. Women’s Health (Lond Engl). 2010 Jan;6(1):119-34. PMID: 20088735.
 
Harris WS. The Omega-3 Index: Clinical Utility for Therapeutic Intervention. Curr Cardiol Rep. 2010 (Sept). 12:503–508. PubMed PMID: 20809235.
 
Ebbesson SOE, Devereux RB, Cole S, Ebbesson LOE, Fabsitz RR, Haack K, Harris WS, Howard WH, Laston S, Lopez-Alvarenga JC, MacCluer JW, Okin PM, Tejero E, Voruganti VS, Wenger CR, Howard BV, Comuzzie AG. Heart Rate is Associated with Red Blood Cell Fatty Acid Concentration: the GOCADAN Study. Am Heart J, 2010;159:1020-1025. PMID: 20569715
Pottala JV, Garg S, Cohen BE, Whooley MA, Harris WS. Blood EPA and DHA Independently Predict All-Cause Mortality in Patients with Stable Coronary Heart Disease. The Heart and Soul Study. Circ:Qual Outcomes 2010;3 406-412. PMID: 20551373
 
Carney RM, Freedland KE, Stein PK, Steinmeyer BC, Harris WS, Rubin EH, Krone RJ, Rich MW. The Effect of Omega-3 Fatty Acids on Heart Rate Variability in Depressed Patients With Coronary Heart Disease. Psychosomat Med 2010;72(8):748-54. PMID: 20716712
 
Ebbesson SO, Tejero ME, López-Alvarenga JC, Harris WS, Ebbesson LO, Devereux RB, MacCluer JW, Wenger C, Laston S, Fabsitz RR, Howard BV, Comuzzie AG. Individual saturated fatty acids are associated with different components of insulin resistance and glucose metabolism: the GOCADAN study. Int J Circumpolar Health. 2010;69:344-51. PMID: 20719107.
 
Lemke SL, Vicini JL, Su H, Goldstein DA, Nemeth MA, Krul ES, Harris WS.  Dietary intake of stearidonic acid enriched soybean oil increases the omega-3 index: randomized, double-blind clinical study of efficacy and safety. Am J Clin Nutr. 2010;92(4):766-75. PMID: 20739419. 
 
Chen J, Shearer GS, Chen Q, Healy CL, Beyer AJ, Nareddy VB, Gerdes AM, Harris WS, O’Connell TD, Wang D. Omega-3 fatty acids prevent pressure overload-induced cardiac fibrosis through activation of cGMP/PKG signaling in cardiac fibroblasts. Circulation 2011;123:584-93. PMID: 21282499.
 
Yang R, Harris WS, Vernon K, Thomas AM, Qureshi N, Morrison DC, Van Way CW 3rd. Pre-feeding with omega-3 fatty acids suppresses inflammation following hemorrhagic shock.  J Parenter Enteral Nutr. 2010 Sep-Oct;34(5):496-502.  PMID: 20852177
 
Skulas-Ray AC, Kris-Etherton PM, Harris WS, Vanden Heuvel JP, Wagner PR, West SG. Dose response effects of omega-3 fatty acids on triglycerides, inflammation, and endothelial function in healthy people with moderate hypertriglyceridemia. Am J Clin Nutr. 2011;93:243-52. PMID:21159789.
 
Larson MK, Shearer GC, Ashmore JH, Anderson-Daniels JM, Graslie EL, Tholen JT, Vogelaar JL, Korth AJ, Nareddy V, Sprehe M, Harris WS. Omega-3 fatty acids modulate collagen signaling in human platelets. Prostaglandins Leukot Essent Fatty Acids. 2011;84:93-8. PMID: 21177087.
 
Hu S, Shearer GC, Steffes MW, Harris WS, Bostom AG. Once-daily extended-release niacin lowers serum phosphorus concentrations in patients with metabolic syndrome dyslipidemia. Am J Kidney Dis. 2011;57:181-2. PMID: 20888102.
 
Aarsetøy H, Aarsetøy R, Lindner T, Staines H, Harris WS, Nilsen DWT. Low Levels of the Omega-3 Index are Associated with Sudden Cardiac Arrest and Remain Stable in Survivors in the Subacute Phase. Lipids 2011;46:151-61. PMID:21234696
 
Moyers B, Farzaneh-Far R, Harris WS, Garg S, Na B, Whooley MA. Relation of Whole Blood n-3 Fatty Acid Levels to Exercise Parameters in Patients With Stable Coronary Artery Disease (from the Heart and Soul Study). Am J Cardiol. 2011;107:1149-54. PMID:21306696
 
Sala-Vila A, Harris WS, Cofán M, Pérez-Heras AM, Pintó X, Lamuela-Raventós RM, Covas M-I, Estruch R, Ros E. Determinants of the omega-3 index in a Mediterranean population at increased risk for coronary heart disease. Brit J Nutr 2011; epub before print March 30. PMID:21450116
 
Billman GE, Harris WS. Effect of Dietary Omega-3 Fatty Acids on the Heart Rate and the Heart Rate Variability Response to Myocardial Ischemia or Submaximal Exercise. Am J Physiol Heart Circ Physiol. 2011 Apr 1. [Epub ahead of print]. PMID:21460198 
 
Salisbury AC, Amin AP, Harris WS, Chan PS, Gosch KL, Rich MW, O'Keefe JH Jr, Spertus JA. Predictors of omega-3 index in patients with acute myocardial infarction. Mayo Clin Proc. 2011 Jul;86(7):626-32.
 
Ladesich JB, Pottala JV, Romaker A, Harris WS. Membrane Level of Omega-3 Docosahexaenoic Acid Is Associated with Severity of Obstructive Sleep Apnea. J Clin Sleep Med 2011; 7:391-396.