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PRESENTATIONS & CONFERENCES

Peter Vitiello was invited to present perinatal grand rounds at the University of Alabama at Birmingham. The title of his talk was “Writing the redox code: thioredoxin signaling in development & disease”

Michael Kareta attended the American Association for Cancer Research – International Association for the Study of Lung Cancer (AACR- IASLC) International Joint Conference on Lung Cancer Translational Science From the Bench to the Clinic in San Diego, CA.

Sam Milanovich attended the 2018 American Society of Hematology meeting in Atlanta, GA.  He met with industry and academic leaders to identify new collaborations and to learn about upcoming clinical trials that may benefit Sanford patients.

Kyle Roux presented recent findings from his laboratory on the nuclear envelope and innate immunity at the annual meeting of the American Society for Cell Biology and European Molecular Biology Organization (ASCB-EMBO) in Philadelphia, PA.

Indra Chandrasekar attended the annual meeting of the American Society for Cell Biology and European Molecular Biology Organization (ASCB-EMBO) in Philadelphia, PA.  The title of her laboratory’s posters were "Development and implementation of a Förster Resonance Energy Transfer based biosensor for measuring intracellular tension and force” and "Nonmuscle myosin-2 isoforms are uniquely expressed in mouse renal epithelial cells and play a critical role in renal tubular function in adult mice".

Kevin Francis gave an invited presentation at the Eunice Kennedy Shriver National Institute of Child Health and Human Development in Bethesda, MD.

Jill Weimer was the keynote speaker at the annual symposium on Lysosomal Storage Disorders in Los Angeles, CA. Dr. Weimer spoke about her lab's work developing therapies for Batten disease.

Jill Weimer organized a research conference in Bethesda, MD focused on management of CLN1 and CLN2 Batten Disease. The “Batten Disease: 2017 Update of Translational Research for Management of INCL/LINCL” conference brought together Batten disease researchers, families, and other academic researchers to discuss how to continue to move Batten research forward. Kevin Francis was invited to present on modeling rare neurological disorders with induced pluripotent stem cells and David Pearce attended.

Randy Faustino attended the annual meeting of the American Heart Association (AHA) in Anaheim, CA. The laboratory presented a poster titled “Embryonic stem cell transcriptome remodeling by a nucleoporin substrate for atrial fibrillation”.

Peter Vitiello attended the annual meeting of the Society for Redox Biology and Medicine (SfRBM) in Baltimore, MD. The laboratory presented a poster titled “Thioredoxin-1 activity is required for embryonic development and perinatal growth”. Dr. Vitiello also participated as an abstract reviewer, judge for young investigator awards and serves on the SfRBM council.

David Pearce was an invited speaker at the annual World Orphan Drug Congress in Barcelona, Spain. Dr. Pearce presented “Integrating rare disease patient registries into electronic health records”, with an overview of the CoRDS registry.

Kamesh Surendran attended the annual meeting of the American Society of Nephrology in New Orleans, LA. The title of his laboratory’s poster was "Maintenance of mature collecting duct principal cells is dependent on Notch signaling".

Michelle Baack was invited to speak at the Exercise and Nutrition Science Seminar Series at the University of New York at Buffalo in Buffalo, NY. The title of her presentation was "Fats and the fetus: you are what your mother eats".

Kyle Roux was invited to speak to physicians and scientists at the Mayo Clinic in Rochester, MN on his research program. The title of his talk was "Tracking protein footprints with BioID".

Daniel Kota was a featured speaker during a TedX talk series in Brookings, SD. Dr. Kota talked about the biology of adult stem cells and how we can use them to treat diseases.

Kyle Roux was invited to speak to the University of Colorado-Boulder Department of Molecular, Cellular, and Developmental Biology. The title of his talk was "Tracking protein footprints with BioID".

Jill Weimer gave an invited presentation at the first annual Children's Tumor Foundation Synodos Network Meeting in Palm Beach, FL. A synodos is a multidisciplinary group of scientists and clinicians working together to solve a unique problem. Dr. Weimer co-leads a multidisciplinary team ) focused on developing a neurofibromatosis type 1 animal model for preclinical drug testing.

Kevin Francis was invited to speak to the South Dakota State University Department of Chemistry & Biochemistry.  Dr. Francis also met with students and faculty to discuss collaborative opportunities with Sanford Research. The title of his talk was "Modeling disorders of sterol biosynthesis with reprogrammed stem cells".

Jill Weimer was invited to speak about her laboratory's gene therapy program at the inaugural Charles River World Congress on Animal Models in Drug Discovery in Boston, MA. This conference discussed how clinical data is used to develop new animal models, tools and developing novel therapies.

Jill Weimer attended the annual Global Genes Summit in Irvine, CA to interact with patient advocacy groups, other researchers, and industry partners to promote Sanford's activities in rare disease research and to initiate new research projects.

David Pearce and Jill Weimer were invited to speak at the annual International Conference on Rare Diseases & Orphan Drugs in Beijing, China.  This conference brings together individuals active in rare diseases and/or orphan drugs across areas of healthcare, research, patient advocacy and public policy.  Dr. Pearce presented on the use of animal models for rare diseases and the integration of natural histories into employee health records for a more accurate diagnosis of rare diseases. Dr. Weimer presented on her laboratory's work on Batten disease that has led to a CLN6 gene therapy program in partnership with Nationwide Children's Hospital.

Michelle Baack attended the annual meeting of the Perinatal Research Society (PRS) in Atlanta, GA. PRS fosters scientific interchange among people with research interests in perinatal medicine and developmental biology.

Jianning Tao attended the annual meeting of the American Society for Bone and Mineral Research (ASBMR) in Denver, CO. The title of his laboratory’s poster was “Differentiation capacity of osteosarcoma cells transformed by distinct oncogenic drivers”.

Lance Lee attended the 2017 PCD on the Move! Conference in Minneapolis, MN.  This meeting was hosted by the Primary Ciliary Dyskinesia (PCD) Foundation and brought together researchers, clinicians, and families to discuss new directions in PCD research and patient care.

Faculty, students and staff from labs of Kevin Francis, Jill Weimer and Haotian Zhao attended the annual Neurobehavioral Research Symposium for the Center for Brain and Behavior Research (CBBRe) at the University of South Dakota.  Dr. Francis moderated the morning session of invited speakers and judged trainee posters. Ruthellen Anderson, Jon Brudvig, Tom Hudson and Katie Grausam had poster presentations.

Alexei Savinov attended the annual meeting of the American Association of Clinical Chemistry in San Diego, CA. The title of his laboratory’s poster was "Investigating the regulatory role of a negative checkpoint molecule, VISTA in endothelial cells".

Michelle Baack was an invited speaker at the FASEB Science Research Conference on Origins and Benefits of Biologically Active Components in Human Milk in Lisbon, Portugal. The title of her talk was "DHA during early development - Building better brains and beyond".

Daniel Kota presented research findings from his lab at the annual meeting for the International Society for Stem Cell Research. The title of his presentation was "Adipose-derived stromal vascular fraction: characterization of the cellular components and therapeutic potential in a murine articular injury model".

Kevin Francis was an invited to present his research findings to both scientists and families at the Smith-Lemli-Optiz (SLO) Scientific Family Medical Conference in Cincinnati, OH. The title of his talks were "Modeling Smith-Lemli-Opitz with pluripotent stem cells" and "SLO Stem Cell Research".

Peter Vitiello was an invited speaker at the 2017 Central Region NIH Institutional Development Award (IDeA) Conference in Sioux Falls, SD. The title of his talk was "Thioredoxin-dependent signaling during redox perturbation".

Kevin Francis and Daniel Kota were invited speakers at the Regenerative Medicine conference at the Sanford Consortium for Regenerative Medicine at USCD in La Jolla, CA.

Peter Vitiello attended a regional meeting of the Society for Redox Biology and Medicine hosted by the University of Alabama-Birmingham Center for Free Radical Biology in Birmingham, AL. 

Kurt Griffin attended the Immunology of Diabetes Society 15th International Congress in San Francisco, CA. The Immunology Diabetes Society provides an international stage for Type 1 Diabetes Research.

Indra Chandrasekar was an invited speaker at the University of South Dakota Department of Biomedical Engineering. The title of her seminar was "Nonmuscle MII takes the center stage in mammalian endocytosis".

 

AWARDS & HONORS

Jill Weimer received a $6,000 grant from the Batten Disease Support & Research Association (BDSRA) to supplement ongoing research investigating therapeutic strategies for Batten disease.

Jianning Tao received a research grant from BioSNTR for engineering a biomimetic nano-structured 3D bone niche for a cancer bone metastasis study.

Jill Weimer received the 2017 Distinguished Researcher Award from the Sanford School of Medicine Department of Pediatrics given to a faculty member who has made significant contributions to the advancement of an area of biomedical, behavioral, or medical research.

Alexei Savinov and Michelle Baack received a Mayo Collaboration grant for "Is the heterogenic mother mitochondrial DNA genome a cause of rejection in transplanted organs from cloned animals?"

Peter Vitiello received a $2 million R01 grant from the National Heart, Lung, and Blood Institute for "Hyperoxic Modulation of Thioredoxin Signaling".

Haotian Zhao received a $1.9 million R01 grant from the National Cancer Institute for "Molecular circuit of multi-ciliogenesis regulates choroid plexus differentiation and tumor development."

Daniel Kota received a research grant from BD Biosciences for "Give me the fats: Charactering and determining the immunosuppressive potential of Tregs and M2 macrophages in the adipose-derived stromal vascular fraction".

Jill Weimer received a T35 training grant for from the Eunice Kennedy Shriver National Institute of Child Health & Human Development for " Developmental Research Program from Medical Students".

Peter Vitiello served on a special emphasis review panel for the National Institutes of Health (NIH). This study section reviewed pulmonary disease-related R01 applications from PIs currently appointed to a standing lung study section.

Alexei Savinov and Kurt Griffin received a research grant from the Sanford Health Foundation for their project titled "Chimeric T regulatory cells for type 1 diabetes treatment".

Sam Milanovich was awarded the 2017 Augustana University Horizon Award, an honor that recognizes early career achievement by an alumnus within 15 years of graduation. 

Sam Milanovich received an equipment grant from Alex’s Lemonade Stand Foundation (ALSF). ALSF is a national childhood cancer foundation dedicated to raising funds for research into new treatments and cures for all children battling cancer. 

Kevin Francis received a subaward from a BioSNTR grant with the Hoppe lab at South Dakota State University to generate macrophages from iPSCs.

Ruthellen Anderson, a MD-PhD candidate in the Francis laboratory, received funding from the Center for Brain and Behavior Research at the University of South Dakota for her dissertation research titled “Dynamic regulation of vesicular trafficking by altered sterol homeostasis in neural cell types”.

 

MEDIA

Peter Vitiello is helping a local family raise awareness and funding for biomedical research on Friedreich’s Ataxia. Their story recently appeared on SDPB, KSOO, KELO, KSFY and in the Argus Leader. https://www.indiegogo.com/projects/the-finish-line-fund#/

Kurt Griffin was interviewed on KSOO's Patrick Lalley Show about Sanford's clinical research efforts on type 1 diabetes and the incresing global incidence of diabetes.  https://soundcloud.com/user-781825766/dr-curt-griffin-sanford-researcher-on-diabetes   

Michelle Baack was featured on KELO news to discuss ongoing projects to understand, prevent, and treat newborn diseases. Dr. Baack discussed Sanford's involvement as one of 15 NIH-selected sites comprising the Neonatal Research Network which allows our neurologists to provide pre-term babies with the newest and most promising therapies.  http://www.keloland.com/news/article/featured-stories/inside-keloland-red-cross-volunteers-sanford-studies

Jill Weimer was interviewed by Dr. Drew on his Weekly Infusion podcast. Dr. Weimer discussed her ongoing gene therapy studies for Batten Disease, a pediatric neurodegenerative disease. http://drdrew.com/2017/wi-38-inside-battens-disease/

Michelle Baack was interviewed by KELO about Sanford's participation in the Neonatal Research Network and how research leads to advancements in care for high-risk babies. Dr. Baack was joined by a family including their 2-year old daughter who was a very premature infant in the Boekelheide NICU.  http://www.keloland.com/news/article/healthbeat/parents-left-with-positive-experience-after-time-at-nicu

 

EXTERNAL SERVICE

Grant Reviews

Kurt Griffin served on a study section reviewing innovative clinical trial grants for a joint funding opportunity sponsored by the Canadian Institutes of Health Research and Juvenile Diabetes Research Foundation (JDRF).

Kurt Griffin served as an ad hoc reviewer for the Department of Defense CDMRP study section on clinical trials for diabetes (CDMRP= Congressionally Directed Medical Research Programs).

Peter Vitiello served on a special emphasis review panel for the National Heart, Lung and Blood Institute.

Jill Weimer was an ad hoc reviewer for the Batten Disease Support and Research Association.

Jill Weimer served on the Neurodevelopment, Synaptic Plasticity, and Neurodegeneration study section panel for the National Institutes of Health (NIH).

Kyle Roux served on a study section panel for the National Institutes of Health Common Fund's 4D Nucleome (4DN) program.

Kamesh Surendran served on a special emphasis panel for the National Institute of Diabetes and Digestive and Kidney Diseases.

Jill Weimer served on the Translational Research in Pediatrics and Obstetric Pharmacology and Therapeutics grant study section for the National Institutes of Health.

 

Outreach & Education

Peter Vitiello was invited to participate in a workshop organized by Project Lead The Way (PLTW) in Indianapolis, IN. PLTW creates STEM learning experiences for K-12 students and Dr. Vitiello reviewed and discussed the PLTW biomedical sciences curriculum with teachers, undergraduate faculty and other health industry representatives.

Kevin Francis participated in a career panel for students at Augustana University and the University of South Dakota for the American Chemical Society's Sioux Valley Local Section meeting. The event was held on the campus of Augustana University and included a student poster session as well.

Jill Weimer presented to participants of the Leadership Sioux Falls course, organized by the Sioux Falls Area Chamber of Commerce. This program fosters the development of leadership in the greater Sioux Falls community. Dr. Weimer spoke about the basic and preclinical research going on in rare diseases at Sanford Research

Committees & Boards

Michelle Baack; NICHD Neonatology Research Network Steering Committee
Michelle Baack; Executive Council of the Midwest Society for Pediatric Research
Michelle Baack; South Dakota Medicaid Advisory Committee
Michelle Baack; Executive Committee of the South Dakota State Medical Association
Kurt Griffin; Program Committee of the Pediatric Endocrine Society
David Pearce; Board of the International Rare Disease Research Consortium
David Pearce; Advisory Board of the Sebastian Velona Foundation
David Pearce; Scientific Advisory Board of the Fight for Batten Foundation
David Pearce; Board of Dakota Lions Sight and Health
David Pearce; Board of the Gwenyth and Charlotte Grey Foundation
David Pearce; Board of the Batten Disease Support and Research Association
David Pearce; Steering Committee of the National Registry for Cell Therapy
David Pearce; Scientific Advisory Board of Xonovo
David Pearce; Scientific Advisory Board of Caladrius
Peter Vitiello; Scientific Advisory Committee of the American Lung Association
Peter Vitiello; Board of the American Lung Association of the Upper Midwest
Peter Vitiello; Board of the South Dakota American Lung Association
Peter Vitiello; Council of the Society for Redox Biology & Medicine
Peter Vitiello; Board of South Dakota STARBASE
Jill Weimer; Board of the South Dakota Bio Association