To meet this objective, the Baack lab research has both a clinical and basic science platforms. Our clinical trials have focused on protecting babies who are born too early. The premature infant is born deficient in omega-3 fatty acids, which are essential for normal health, brain and retinal development. A clinical trial in the Boekelheide NICU focuses on developing new ways to overcome this deficiency with the goal to prevent significant complications of prematurity.
|Access Dr. Baack's publications here.|
|Meet members of the Baack lab here.|
|Phone: (605) 312-6420||View news about Baack lab here.|
|Fax: (605) 312-6071|
March 2016, Dr. Michelle Baack’s recent publication entitled “Maternal high-fat diet impairs cardiac function in offspring of diabetic pregnancy through metabolic stress and mitochondrial dysfunction” in the journal American Journal of Physiology - Heart and Circulatory Physiology has been nominated for distinction in scholarship for APS select This is a collection of articles from the APS journals that showcases some of the best recently published articles in physiological research.
February 2016, Dr. Michelle Baack and her team have recently published a study entitled “Daily Enteral DHA Supplementation Alleviates Deficiency in Premature Infants” in the journal Lipids. This randomized, clinical trial demonstrates that premature infants receiving standard neonatal nutrition remained deficient in docosahexaenoic acid (DHA) throughout their hospitalization, but supplementation with 50mg/d of enteral DHA was well tolerated and alleviated deficiency. Coauthors on this publication included Michelle L Baack, Susan E Puumala, Stephen E Messier, Deborah K Pritchett, and William S Harris.
January 2016, Dr. Michelle Baack’s team recently had a publication in the American Journal of Physiology – Heart and Circulatory Physiology entitled “Maternal high-fat diet impairs cardiac function in offspring of diabetic pregnancy through metabolic stress and mitochondrial dysfunction.” Sanford co-authors on the publication include Dr. Kenney Mdaki, Tricia Larsen, Dr. Michelle Schimelpfenig, Angela Wachel and Sam Dooyema as well as USD medical student Lucinda J Weaver and Augustana undergraduate Eli J Louwagie. This study is the first to demonstrate that a maternal high-fat diet further impairs cardiac function in offspring of diabetic pregnancy through metabolic abnormalities, oxidative stress and mitochondrial dysfunction. Findings serve as a critical step in understanding the role of cellular bioenergetics in developmentally programmed cardiac disease.
January 2016, Dr. Michelle Baack will be an invited presenter at Perinatal Grand Rounds at the University of Alabama on January 20th. The title of her talk will be “Fats and the fetus: You are what your mother eats.”