Pearce Lab

Pearce Lab for Genetically Inherited Diseases of Children

The Pearce lab has a general interest in genetically inherited diseases of children. More specifically our goal is to contribute to the understanding of the molecular basis of several pediatric neurodegenerative diseases.

Batten Disease

The disease that is our primary focus is Batten disease. Batten disease is a type of Neuronal Ceroid Lipofuscinosis, so called because of the fact that a part of the cell called the lysosome accumulates a heterogeneous mix of fat-like material called lipofuscin. Many other diseases that result in brain degenerative diseases in children result from accumulation of other biological compounds in the lysosome. These are collectively termed Lysosomal Storage Disorders. Through exploration of our website you will find that we are interested in these other Lysosomal Storage Disorders also, but resources and ideas currently limit us to focus most of our efforts on Batten disease.

Additional Information on Pearce Lab Research

Lecture on JNCL Research by Dr. David Pearce

Donate to Batten Research

Contact Information for Pearce Lab:

David A. Pearce
President of Research, Sanford Health
Senior Scientist, Children’s Health Research Center
Professor, Department of Pediatrics, Sanford School of Medicine of the University of South Dakota

2301 E 60th Street North | Sioux Falls, SD 57104

PHONE: 605-312-6004
FAX: 605-328-0401